Table 2 The types of problems, interventions and acceptance of DRPs according to the PCNE classification V9.1

Problems

254 (100)

144 (100)

110 (100)

P1

Treatment effectiveness

78 (30.7)

20 (13.9)

58 (52.7)

P1.1

No effect of drug treatment despite correct use

1 (0.4)

-

1 (0.9)

P1.2

Effect of drug treatment not optimal

64 (25.2)

20 (13.9)

44 (40.0)

P1.3

Untreated symptoms or indication

13 (5.1)

-

13 (11.8)

P2

Treatment safety

170 (66.9)

124 (86.1)

46 (41.8)

P2.1

Adverse drug event (possibly) occurring

170 (66.9)

124 (86.1)

46 (41.8)

P3

Other

6 (2.4)

-

6 (5.5)

P3.1

Unnecessary drug-treatment

6 (2.4)

-

6 (5.5)

Interventions

292 (100)

154 (100)

138 (100)

I1

At prescriber level

165 (56.5)

143 (92.9)

22 (15.9)

I1.3

Intervention proposed to prescriber

144 (49.3)

132 (85.7)

12 (8.7)

I1.4

Intervention discussed with prescriber

21 (7.2)

11 (7.1)

10 (7.2)

I2

At patient level

110 (37.7)

11 (7.1)

99 (71.7)

I2.1

Patient (drug) counselling

43 (14.7)

11 (7.1)

32 (23.2)

I2.2

Written information provided (only)

24 (8.2)

-

24 (17.4)

I2.3

Patient referred to prescriber

43 (14.7)

-

43 (31.2)

I3

At drug level

16 (5.5)

-

16 (11.6)

I3.4

Instructions for use changed to …

9 (3.1)

-

9 (6.5)

I3.5

Drug paused or stopped

7 (2.4)

-

7 (5.1)

I4

Other intervention or activity

1 (0.3)

-

1 (0.7)

I4.2

Side effect reported to authorities

1 (0.3)

-

1 (0.7)

Acceptance

292 (100)

154 (100)

138 (100)

A1

Intervention accepted

285 (97.6)

154 (100)

131 (94.9)

A1.1

Intervention accepted and fully implemented

209 (71.6)

143 (92.9)

66 (47.8)

A1.2

Intervention accepted, partially implemented

1 (0.3)

-

1 (0.7)

A1.3

Intervention accepted but not implemented

10 (3.4)

-

10 (7.2)

A1.4

Intervention accepted, implementation unknown

65 (22.2)

11 (7.1)

54 (39.1)

A2

Intervention not accepted

7 (2.4)

-

7 (5.1)

A2.2

Intervention not accepted: no agreement

7 (2.4)

-

7 (5.1)