Table 4 Breakdown of the base-case results

Clinical outcomes (%)

 Cure rate (1^st)

60.6

57.1

 Cure rate (2^nd)

56.8

52.8

 Mortality rate (1^st)

20.1

25.5

 Mortality rate (2^nd)

24.1

30.6

 AE rate (Septic shock)

3.6

4.7

 AE rate (Multiorgan failure)

3.9

2.8

 AE rate (Cardiac failure acute)

2.5

2.2

 AMK related AE rate (Acute renal failure)

6

6

QALYs

2.35

2.18

Cost estimates (Yen)

 Drug (1^st)

291,312

21,307.47

 Drug (2^nd)

259,896

23,121

 Hospitalization (1^st)

2,136,960

2,063,280

 Hospitalization (2^nd)

350,340

358,020

 Mechanical ventilation (1^st)

114,000

123,500

 Mechanical ventilation (2^nd)

97,800

97,800

 AE treatment (1^st)

42,435.33

41,887.05

 AE treatment (2^nd)

48,123.33

47,575.05

 Long-term care in ICU

495,000

495,000

 Long-term care in ward

495,000

495,000