Table 2 Results of the base case, sensitivity and scenario analysis for the comparison between Intraoperative radiation therapy (IORT) and Intensity-modulated radiation therapy (IMRT). Expected benefits and costs, together with the corresponding ICER, are reported for each case and outcome
IORT | IMRT | Incremental | ICER | |
|---|---|---|---|---|
Base case | ||||
LYs | 8.48 | 8.48 | −0.002 | −$426,358 |
RFLYs | 7.92 | 8.19 | −0.27 | −$3,733 |
QALYs | 7.69 | 7.75 | −0.05 | −$19,095 |
QARFLYs | 7.29 | 7.53 | −0.25 | −$4,058 |
Costs | $1,330 | $323 | $1,006 | – |
Sensitivity analysis | ||||
IORT lower recurrence | ||||
LYs | 8.48 | 8.48 | −0.002 | −$432,972 |
RFLYs | 8.01 | 8.19 | −0.18 | −$5,531 |
QALYs | 7.71 | 7.75 | −0.04 | −$25,309 |
QARFLYs | 7.37 | 7.53 | −0.17 | −$6,012 |
Costs | $1,330 | $323 | $1,006 | – |
IORT lower metastasis | ||||
LYs | 8.48 | 8.48 | −0.002 | −$566,948 |
RFLYs | 7.99 | 8.19 | −0.20 | −$4,939 |
QALYs | 7.71 | 7.75 | −0.04 | −$27,438 |
QARFLYs | 7.35 | 7.53 | −0.19 | −$5,369 |
Costs | $1,330 | $323 | $1,006 | – |
Scenario analysis | ||||
LYs | 8.48 | 8.48 | −0.002 | −$191,905 |
RFLYs | 7.92 | 8.19 | −0.27 | −$1,680 |
QALYs | 7.69 | 7.75 | −0.05 | −$8,595 |
QARFLYs | 7.29 | 7.53 | −0.25 | −$1,826 |
Costs | $776 | $323 | $453 | – |