Table 1 Model parameters for Intraoperative radiation therapy (IORT) and Intensity-modulated radiation therapy (IMRT)

Transition probabilities

LR after BCS year 1

0.000

0.002

0.000

[7, 11]

LR after BCS year 2

0.001

0.004

0.000

[7, 11]

LR after BCS year 3

0.018

0.004

0.010

[7, 11]

LR after BCS year 4

0.009

0.011

0.008

[7, 11]

LR after BCS year 5

0.005

0.000

0.006

[7, 11]

LR after BCS year 6

0.016

0.000

0.011

[7, 11]

LR after BCS year 7

0.001

0.004

0.002

[7, 11]

LR after BCS year 8

0.012

0.008

0.010

[7, 11]

LR after BCS year 9

0.010

0.000

0.008

[7, 11]

LR after BCS year 10

0.006

0.000

0.005

[7, 11]

Metastasis after LR

0.03

0.03

–

[16]

Metastasis after RF

0.006

0.0029

0.004

[7, 11]

Death by any cause 50–54

0.002

[15]

Death by any cause 55–59

0.004

[15]

Death by any cause 60–64

0.006

[15]

Death by any cause 65–69

0.009

[15]

Death by breast cancer year 1

0.003

0.004

[7, 11]

Death by breast cancer year 2

0.002

0.004

[7, 11]

Death by breast cancer year 3

0.006

0.006

[7, 11]

Death by breast cancer year 4

0.008

0.006

[7, 11]

Death by breast cancer year 5

0.017

0.006

[7, 11]

Death by breast cancer year 6

0.018

0.003

[7, 11]

Death by breast cancer year 7

0.006

0.012

[7, 11]

Death by breast cancer year 8

0.011

0.010

[7, 11]

Death by breast cancer year 9

0.008

0.017

[7, 11]

Death by breast cancer year 10

0.018

0.005

[7, 11]

Costs

Treatment cost

$418

$29

–

Other direct cost

$359

$294

–

Annual maintenance cost

$55,344

–

–

Health state utilities

Disease free

0.920

[17]

Local recurrence

0.779

[17]

Other recurrences

0.685

[17]