Table 4b Mean and total cost of CAR-T clinical pathway by phase: AOU Careggi
From: Cost of implementing CAR-T activity and managing CAR-T patients: an exploratory study
Clinical pathway phases | # of patients | Mean cost per patient | % | Total cost | % |
|---|---|---|---|---|---|
Patients eligibility check | 27 | € 1,429 | 9% | € 38,579 | 13% |
Evaluation and confirmation of eligibility / patients enrollment | 17 | € 2,771 |  | € 47,099 |  |
Lymphocytoapheresis planning and execution / Lymphocyte engineering procedure and bag delivery | 17 | € 1,103 |  | € 18,744 |  |
Bridge therapy (radiotherapy (10) or chemotherapy (2)) and bag reception | 12 | € 1,701 |  | € 20,417 |  |
Outpatient prelymphodepletion and lymphodepletion | 2 | € 423 |  | € 5,078 |  |
Inpatient episode: Lymphodepletion and infusion | 12 | € 61,812 | 74% | € 741,740 | 74% |
Follow up (+ 30 days) | 11 | € 3,373 | 17% | € 37,103 | 13% |
Follow up (+ 60 days) | 11 | € 1,132 |  | € 12,449 |  |
Follow up (+ 90 days) | 11 | € 2,388 |  | € 26,265 |  |
Follow up (+ 120 days) | 9 | € 547 |  | € 4,921 |  |
Follow up (+ 180 days) | 9 | € 2,678 |  | € 24,100 |  |
Follow up (+ 365 days) | 5 | € 4,129 |  | € 20,644 |  |
Total (patients living after a follow-up of one year) | 5 | € 83,484 | 100% | € 997,138 | 100% |
Total (patients reported as eligible) | 27 | € 36,931 |  |  |  |