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Table 4a Mean and total cost of CAR-T clinical pathway by phase: IRCCS AOU BO Orsola

From: Cost of implementing CAR-T activity and managing CAR-T patients: an exploratory study

Clinical pathway phases

# of patients

Mean cost per patient

%

Total cost

%

Analysis of patient eligibility

59

€54

9%

€3,164

14%

Assessment of patient eligibility

52

€858

€44,623

Consent form management, Drug choice, Communication to the relevant pharmaceutical companies

52

€284

€14,778

Apheresis planning

52

€2,499

€129,972

Apheresis / Therapy Request Procedure

44

€650

€28,621

Pre-hospitalization / Lymphocyte engineering process

36

€4,516

€162,570

Inpatient episode: Lymphocyte reception / Hospitalization / Bridge therapy / Infusion / Monitoring / Toxicity management

29

€67,033

71%

€1,943,960

71%

Discharge

27

€226

20%

€6,101

15%

Follow-up (+ 30 days)

24

€11,623

€278,952

Follow up (+ 120 days)

21

€6,955

€146,053

Total (living patients after 120 days of follow-up)

21

€94,699

100%

€2,758,793

100%

Total (patients reported as eligible)

59

€46,759

  1. Source: Primary data (interviews with the CAR-T coordinators) and secondary data (e.g. personnel costs, fee-for-episode and service) collected at the IRCCS AOU BO Orsola