Characteristics | By opioid use group | p-value | ||
---|---|---|---|---|
No use (n = 910) | Opioid use (n = 100) | PIOU (n = 191) | ||
Patient | ||||
Age, n (%) | ||||
65–74 years | 583 (64.1) | 66 (66.0) | 111 (58.1) | 0.252 |
75 + years | 327 (35.9) | 34 (34.0) | 80 (41.9) | |
Sex, n (%) | ||||
Male | 392 (43.1) | 60 (60.0) | 54 (28.3) | < 0.001* |
Female | 518 (56.9) | 40 (40.0) | 137 (71.7) | |
Marital status, n (%) | ||||
Married/ in common law | 582 (64.2) | 68 (68.0) | 117 (61.6) | 0.551 |
Single/divorced/widowed | 324 (35.8) | 32 (32.0) | 73 (38.4) | |
Education level, n (%) | ||||
Primary | 214 (23.5) | 30 (30.0) | 50 (26.2) | 0.198 |
Secondary | 394 (43.3) | 46 (46.0) | 89 (46.6) | |
Post-secondary/university | 302 (33.2) | 24 (24.0) | 52 (27.2) | |
Country of origin, n (%) | ||||
Canada | 880 (96.8) | 95 (95.0) | 176 (92.1) | 0.011* |
Other (immigrant) | 29 (3.2) | 5 (5.0) | 15 (7.9) | |
Annual household income, n (%) | ||||
< $25,000 | 282 (31.0) | 28 (28.0) | 71 (37.2) | 0.175 |
≥ $25,000 | 628 (69.0) | 72 (72.0) | 120 (62.8) | |
Social support index, score 0–3, mean (SD) | 2.78 (SD: 0.63) | 2.76 (SD: 0.67) | 2.73 (SD: 0.72) | 0.705 |
Number of daily hassles, score 0–22, mean (SD) | 4.61 (SD: 3.88) | 3.88 (SD: 3.66) | 5.24 (SD: 3.62) | 0.013* |
K10 Psychological distress, score 10–50, mean (SD) | 17.98 (SD: 7.01) | 17.07 (SD: 6.47) | 20.87 (SD: 7.83) | < 0.001* |
Presence of traumatic events, n (%) | ||||
Childhood | 115 (12.6) | 10 (10.2) | 29 (15.8) | 0.387 |
Sexual abuse, assault, violence, stalked, kidnapping, war/combat | 239 (26.8) | 24 (24.5) | 61 (33.2) | 0.165 |
Other (accident, natural disaster, life-threatening disease) | 454 (50.9) | 49 (50.0) | 107 (58.2) | 0.184 |
Multimorbidity, n (%) | ||||
0–2 chronic physical conditions + no common mental disorder | 114 (13.0) | 13 (13.8) | 7 (3.9) | 0.001* |
0–2 chronic physical conditions + ≥ 1 common mental disorder | 35 (4.0) | 2 (2.1) | 5 (2.8) | |
≥ 3 chronic physical conditions + no common mental disorder | 467 (53.2) | 61 (64.9) | 96 (53.3) | |
≥ 3 chronic physical conditions + ≥ 1 common mental disorder | 262 (29.8) | 18 (19.1) | 72 (40.0) | |
Health service use, mean (SD) | ||||
Outpatient visits in 3 months before opioid use or PIOU | 1.72 (SD: 1.71) | 1.51 (SD: 1.19) | 3.78 (SD: 5.72) | < 0.001* |
Hospitalizations in 3 years before opioid use or PIOU | 1.22 (SD: 2.00) | 1.18 (SD: 2.31) | 2.55 (SD: 3.04) | < 0.001* |
Emergency department visits in 3 years before opioid use or PIOU | 0.91 (SD: 1.63) | 0.77 (SD: 1.44) | 2.20 (SD: 2.49) | < 0.001* |
Pain | ||||
Pain severity, n (%) | < 0.001* | |||
No/low pain | 508 (56.8) | 57 (57.6) | 84 (45.4) | |
Moderate pain | 360 (40.3) | 38 (38.4) | 79 (42.7) | |
Extreme pain | 26 (2.9) | 4 (4.0) | 22 (11.9) | |
Pain type, n (%) | ||||
Inflammatory | 224 (24.6) | 19 (19.0) | 80 (41.9) | < 0.001* |
Nociceptive | 93 (10.2) | 4 (4.0) | 51 (26.7) | < 0.001* |
Neuropathic | 69 (7.6) | 13 (13.0) | 28 (14.7) | 0.003* |
Nociplastic | 50 (5.5) | 1 (1.0) | 12 (6.3) | 0.125 |
Other | 45 (4.9) | 3 (3.0) | 16 (8.4) | 0.088† |
Substance use | ||||
Substance or alcohol use disorder | ||||
Absence | 837 (92.0) | 98 (98.0) | 168 (88.0) | 0.012* |
Presence | 73 (8.0) | 2 (2.0) | 23 (12.0) | |
Alcohol use | 0.907 | |||
Non-drinkers | 225 (25.3) | 25 (25.3) | 46 (24.9) | |
Light to moderate drinkers | 622 (69.9) | 68 (68.7) | 127 (68.6) | |
Heavy drinkers | 43 (4.8) | 6 (6.1) | 12 (6.5) | |
Provider | ||||
Number of distinct prescribers in 3 years before opioid use or PIOU, mean (SD) | 3.45 (SD: 2.73) | 3.90 (SD: 2.65) | 5.88 (SD: 3.64) | < 0.001* |
Continuity of care index, mean (SD) | 0.24 (SD: 0.24) | 0.19 (SD: 0.21) | 0.21 (SD: 0.23) | 0.083† |
Health care system | ||||
Type of practice, n (%) | ||||
FMG or CLSC | 361 (40.0) | 53 (54.1) | 83 (43.7) | 0.024* |
Private clinic with < 3 physicians | 273 (30.3) | 23 (23.5) | 43 (22.6) | |
Private clinic with ≥ 3 physicians | 268 (29.7) | 22 (22.4) | 64 (33.7) |