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Table 4 Results of linear mixed model assessing factors associated with the three dimensions of quality of life: QUALID sadness, tension, and well-being a

From: Pain and quality of life in nursing home residents with dementia after admission – a longitudinal study

 

QUALID sadness Adjusted model

QUALID tension Adjusted model

QUALID well-being Adjusted model

RC (95% CI)

p-value

RC (95% CI)

p-value

RC (95% CI)

p-value

Time (months)

 0

0

 

0

 

0

 

 12

0.002 (-0.22; 0.22)

0.985

-0.15 (-0.39; 0.10)

0.240

0.16 (-0.04; 0.37)

0.123

 24

-0.09 (-0.37; 0.19)

0.542

-0.01 (-0.33; 0.30)

0.932

0.23 (-0.04; 0.49)

0.100

Assessed simultaneously with outcome

 MOBID-2

0.03 (0.02; 0.04)

 < 0.001

0.05 (0.03; 0.06)

 < 0.001

0.004 (-0.007; 0.02)

0.440

 CDR-SoB

0.05 (0.01; 0.10)

0.008

0.08 (0.03; 0.12)

0.001

0.04 (-0.004; 0.08)

0.074

GMHR

 Poor/Fairly poor– ref

0

 

0

 

0

 

 Good/Fairly good

-0.09 (-0.31; 0.13)

0.426

-0.15 (-0.39; 0.09)

0.218

-0.26 (-0.48; -0.04)

0.022

 PSMS

0.03 (-0.003; 0.06)

0.077

0.07 (0.03; 0.10)

 < 0.001

0.11 (0.08; 0.14)

 < 0.001

NPI-NH sub-syndromeb

 Agitation

0.007 (-0.01; 0.02)

0.433

0.20 (0.18; 0.22)

 < 0.001

0.02 (-0.001; 0.03)

0.066

 Affective

0.29 (0.27; 0.32)

 < 0.001

0.21 (0.18; 0.24)

 < 0.001

0.06 (0.04; 0.08)

 < 0.001

 Psychosis

0.01 (-0.02; 0.04)

0.445

0.05 (0.01; 0.08)

0.005

0.001 (-0.03; 0.03)

0.925

 Apathy

0.08 (0.03; 0.12)

0.001

-0.02 (-0.07; 0.03)

0.346

0.26 (0.22; 0.31)

 < 0.001

Psychotropic drugs (number)

  0 – ref

0

 

0

 

0

 

  1

0.20 (-0.05; 0.46)

0.117

0.09 (-0.19; 0.36)

0.547

-0.03 (-0.28; 0.22)

0.830

  2

0.39 (0.08; 0.70)

0.013

0.23 (-0.11; 0.56)

0.183

0.14 (-0.17; 0.45)

0.382

  3+ 

0.46 (0.04; 0.88)

0.030

0.42 (-0.03; 0.87)

0.070

0.26 (-0.17; 0.68)

0.235

Analgesics

      

 Opioidsc

0.14 (-0.14; 0.42)

0.339

0.39 (0.08; 0.70)

0.013

0.18 (-0.10; 0.46)

0.211

 Paracetamold

0.25 (0.02; 0.48)

0.035

0.36 (0.11; 0.61)

0.005

0.02 (-0.21; 0.25)

0.852

Civil status

 Unmarried/no partner – ref

0

 

0

 

0

 

 Married/partner

0.14 (-0.14; 0.41)

0.328

0.24 (-0.05; 0.53)

0.108

0.009 (-0.27; 0.29)

0.950

Assessed at baseline

 Age

-0.0005 (-0.02; 0.02)

0.953

0.0007 (-0.02; 0.02)

0.936

0.008 (-0.01; 0.02)

0.392

Gender

 Females – ref

0

 

 

0

 

 Males

-0.42 (0.68; -0.17)

0.001

-0.12 )-0.39; 0.16)

0.404

0.14 (-0.13; 0.41)

0.315

 NH

      

 Regular care unit – ref

0

 

0

 

0

 

 Special care unit

0.24 (-0.02; 0.49)

0.070

0.08 (-0.19; 0.35)

0.555 

-0.64 (-0.91; -0.37)

 < 0.001

  1. Bold values shown statistically significant result with a p-value less than 0.05
  2. Abbreviations: CI Confidence interval, CDR-SoB Clinical Dementia Rating–Sum of Boxes, GMHR General Medical Health Rating, MOBID-2 Mobilization-Observation-Behavior-Intensity-Dementia-2, NH Nursing Home, NPI-NH Neuropsychiatric Inventory Nursing Home version, PSMS Physical Self- Maintenance Scale, RC Regression coefficient, QUALID Quality of Life of Late Stage Dementia
  3. aResults of linear mixed model analyses. All analyses adjusted for cluster effect within NH; Only cases with no missing values on adjustment variables are included in the analyses
  4. QUALID well-being dimension includes: smiles, enjoys eating, enjoys social interaction and enjoys touching/being touched, QUALID tension dimension includes: physically uncomfortable, verbalization suggests discomfort, irritable and appears calm, QUALID well-being dimension includes: smiles, enjoys eating, enjoys social interaction and enjoys touching/being touched
  5. N = 823 (A1) + 519 (A2) + 299 (A3) = 1641
  6. bNPI-NH Agitation sub-syndrome: agitation/aggression, disinhibition and irritability; NPI-NH Affective sub-syndrome: depression and anxiety; NPI-NH Psychosis sub-syndrome: delusions and hallucination
  7. cOpioids N02A
  8. dParacetamol N02B E01, N02A J06, and N02A J13