QUALID sadness Adjusted model | QUALID tension Adjusted model | QUALID well-being Adjusted model | ||||
---|---|---|---|---|---|---|
RC (95% CI) | p-value | RC (95% CI) | p-value | RC (95% CI) | p-value | |
Time (months) | ||||||
0 | 0 | 0 | 0 | |||
12 | 0.002 (-0.22; 0.22) | 0.985 | -0.15 (-0.39; 0.10) | 0.240 | 0.16 (-0.04; 0.37) | 0.123 |
24 | -0.09 (-0.37; 0.19) | 0.542 | -0.01 (-0.33; 0.30) | 0.932 | 0.23 (-0.04; 0.49) | 0.100 |
Assessed simultaneously with outcome | ||||||
MOBID-2 | 0.03 (0.02; 0.04) | < 0.001 | 0.05 (0.03; 0.06) | < 0.001 | 0.004 (-0.007; 0.02) | 0.440 |
CDR-SoB | 0.05 (0.01; 0.10) | 0.008 | 0.08 (0.03; 0.12) | 0.001 | 0.04 (-0.004; 0.08) | 0.074 |
GMHR | ||||||
Poor/Fairly poor– ref | 0 | 0 | 0 | |||
Good/Fairly good | -0.09 (-0.31; 0.13) | 0.426 | -0.15 (-0.39; 0.09) | 0.218 | -0.26 (-0.48; -0.04) | 0.022 |
PSMS | 0.03 (-0.003; 0.06) | 0.077 | 0.07 (0.03; 0.10) | < 0.001 | 0.11 (0.08; 0.14) | < 0.001 |
NPI-NH sub-syndromeb | ||||||
Agitation | 0.007 (-0.01; 0.02) | 0.433 | 0.20 (0.18; 0.22) | < 0.001 | 0.02 (-0.001; 0.03) | 0.066 |
Affective | 0.29 (0.27; 0.32) | < 0.001 | 0.21 (0.18; 0.24) | < 0.001 | 0.06 (0.04; 0.08) | < 0.001 |
Psychosis | 0.01 (-0.02; 0.04) | 0.445 | 0.05 (0.01; 0.08) | 0.005 | 0.001 (-0.03; 0.03) | 0.925 |
Apathy | 0.08 (0.03; 0.12) | 0.001 | -0.02 (-0.07; 0.03) | 0.346 | 0.26 (0.22; 0.31) | < 0.001 |
Psychotropic drugs (number) | ||||||
0 – ref | 0 | 0 | 0 | |||
1 | 0.20 (-0.05; 0.46) | 0.117 | 0.09 (-0.19; 0.36) | 0.547 | -0.03 (-0.28; 0.22) | 0.830 |
2 | 0.39 (0.08; 0.70) | 0.013 | 0.23 (-0.11; 0.56) | 0.183 | 0.14 (-0.17; 0.45) | 0.382 |
3+ | 0.46 (0.04; 0.88) | 0.030 | 0.42 (-0.03; 0.87) | 0.070 | 0.26 (-0.17; 0.68) | 0.235 |
Analgesics | ||||||
Opioidsc | 0.14 (-0.14; 0.42) | 0.339 | 0.39 (0.08; 0.70) | 0.013 | 0.18 (-0.10; 0.46) | 0.211 |
Paracetamold | 0.25 (0.02; 0.48) | 0.035 | 0.36 (0.11; 0.61) | 0.005 | 0.02 (-0.21; 0.25) | 0.852 |
Civil status | ||||||
Unmarried/no partner – ref | 0 | 0 | 0 | |||
Married/partner | 0.14 (-0.14; 0.41) | 0.328 | 0.24 (-0.05; 0.53) | 0.108 | 0.009 (-0.27; 0.29) | 0.950 |
Assessed at baseline | ||||||
Age | -0.0005 (-0.02; 0.02) | 0.953 | 0.0007 (-0.02; 0.02) | 0.936 | 0.008 (-0.01; 0.02) | 0.392 |
Gender | ||||||
Females – ref | 0 | 0 | 0 | |||
Males | -0.42 (0.68; -0.17) | 0.001 | -0.12 )-0.39; 0.16) | 0.404 | 0.14 (-0.13; 0.41) | 0.315 |
NH | ||||||
Regular care unit – ref | 0 | 0 | 0 | |||
Special care unit | 0.24 (-0.02; 0.49) | 0.070 | 0.08 (-0.19; 0.35) | 0.555 | -0.64 (-0.91; -0.37) | < 0.001 |