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Table 2 The mean effectiveness rates and costs of Natalizumab, and Rituximab

From: Clinical and economic evaluations of natalizumab, rituximab, and ocrelizumab for the management of relapsing-remitting multiple sclerosis in Saudi Arabia

Difference in Cost and Effectiveness Rate between Natalizumab and Rituximab

 

Natalizumab

Rituximab

Mean difference (95% confidence interval)

Cost of treatment (USD), mean ± SD

50,843.5 ± 32,625.9

15,460.1 ± 12,969.2

35,383.4(25,401.1–49,717.9)

Effectiveness rate (%),† mean ± SD

72.0 ± 45.4

76.9 ± 42.9

-4.92(-30–27.5)

  1. † Effectiveness is measured as the reduction in the rate of disease progression as assessed by NEDA-3. Costs included all direct medical costs (e.g., drug acquisition price, lab tests, imaging studies, etc.…) retrieved from the Saudi Ministry of Health cost center