Overall sample (n = 45 542) | British Columbia Generations Project (n = 13 786) | Alberta’s Tomorrow Project (n = 7 518) | Ontario Health Study (n = 9 652) | Quebec’s CARTaGENE (n = 5 186) | Atlantic PATH (n = 9 400) | |
---|---|---|---|---|---|---|
aOR (95% CI)* | aOR (95% CI)* | aOR (95% CI)* | aOR (95% CI)* | aOR (95% CI)* | aOR (95% CI)* | |
Predisposing factors | ||||||
CanPath Regional cohorts | ||||||
British Columbia Generations Project (BCGP) | 1.73 (1.41, 2.12) | |||||
Alberta’s Tomorrow Project (ATP) | 1.07 (0.89, 1.28) | |||||
Ontario Health Study (OHS) | 1.26 (1.02, 1.56) | |||||
Quebec’s CARTaGENE (CaG) | 1.00 | |||||
Atlantic PATH | 1.39 (1.13, 1.72) | |||||
Age group | ||||||
< 44 years | 3.02 (2.51, 3.62) | 4.15 (2.63, 6.56) | 3.43 (2.27, 5.19) | 2.73 (1.95, 3.81) | - | 2.42 (1.68, 3.49) |
45–54 years | 2.65 (2.34, 3.00) | 2.81 (2.26, 3.49) | 3.02 (2.18, 4.19) | 2.38 (1.80, 3.13) | 2.47 (1.57, 3.87) | 2.42 (1.85, 3.16) |
55–64 years | 1.84 (1.66, 2.05) | 1.95 (1.64, 2.33) | 1.89 (1.40, 2.55) | 1.68 (1.32, 2.13) | 1.90 (1.32, 2.73) | 1.74 (1.37, 2.20) |
≥ 65 years | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Gender identity | ||||||
Male | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Female | 1.37 (1.24, 1.52) | 1.23 (1.03, 1.47) | 1.25 (0.98, 1.58) | 2.00 (1.59, 2.52) | 1.08 (0.78, 1.48) | 1.35 (1.08, 1.70) |
Other gender minority | 2.16 (1.16, 4.03) | 1.34 (0.34, 5.36) | 2.56 (0.48, 13.66) | 2.03 (0.64, 6.49) | 1.09 (0.14, 8.48) | 5.64 (1.52, 20.91) |
Race/ethnicity: Caucasian vs. non-Caucasian | 1.12 (0.93, 1.35) | 1.50 (1.10, 2.04) | 1.06 (0.66, 1.71) | 0.88 (0.64, 1.22) | 0.76 (0.39, 1.47) | 1.02 (0.51, 2.02) |
Current smoking | ||||||
Yes vs. No | 0.86 (0.71. 1.04) | 1.05 (0.70, 1.58) | 0.62 (0.37, 1.03) | 0.72 (0.48, 1.09) | 1.34 (0.83, 2.17) | 0.81 (0.57, 1.15) |
Past-year cannabis use | ||||||
Yes vs. No | 1.33 (1.20, 1.48) | 1.23 (1.01, 1.49) | 1.30 (1.01, 1.67) | 1.47 (1.18, 1.83) | 1.12 (0.70, 1.80) | 1.41 (1.15, 1.74) |
Past-year average weekly alcohol consumption | ||||||
Never | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Less than Daily (≤ 5 times/week) | 0.75 (0.67, 0.85) | 0.74 (0.60, 0.92) | 0.79 (0.59, 1.05) | 0.64 (0.50, 0.83) | 0.64 (0.40, 1.00) | 0.90 (0.70, 1.17) |
Almost daily (Six to seven times a week | 0.67 (0.56, 0.79) | 0.55 (0.41, 0.73) | 0.72 (0.46, 1.12) | 0.72 (0.51, 1.03) | 0.50 (0.27, 0.93) | 0.84 (0.56, 1.26) |
Model C statistic | 0.804 | 0.798 | 0.813 | 0.823 | 0.796 | 0.802 |