Table 4 Overview of sample sizes and drop-outs

Deprexis

Study 1 [17]

163

78

85

29 (17.8%)

17

12

45 (27.6%)

21

24

Study 2 [18]

1013

509

504

219 (21.6%)

114

105

259 (25.6%)

131

128

Elevida [19]

275

139

136

51 (18.5%)

36

15

64 (23.3%)

44

20

Hello Better

Diabetes and Depression [20, 21]

254

128

126

47 (18.5%)

31

16

74 (29.1%)

50

24

Hello Better

Panik [22, 23]

92

45

47

8 (8.7%)

4

4

20 (21.7%)

10

10

Hello Better

Stress und Burnout [24, 25]

264

132

132

21 (8.0%)

16

5

51 (19.3%)

40

11

Hello Better

Vaginismus Plus [26, 27]

200

100

100

30 (15.0%)

22

8

51 (25.5%)

42

9

Kalmeda [28]

187

94

93

24 (12.8%)

16

8

92 (48.9%)

41

51

Selfapy Depression [29]

401

IG1 = 151

IG2 = 150

100

95 (23.7%)

IG1 = 19

IG2 = 30

46

246 (61.3%)

IG1 = 87

IG2 = 88

71

Somnio [30]

56

29

27

4 (7.1%)

4

0

3 (5.4%)

3

0

Velibra [31]

139

70

69

19 (13.7%)

13

6

26 (37.0%)

26

n.a

Vivira [32]

RCT

215

2

n.r

n.r

n.r

n.r

n.r

n.r

n.r

Pre-Post-Study

hip = 256

knee = 402

n.r

n.r

hip = 242 (94.5%)

knee = 372 (92.5%)

n.r

n.r

n.r

n.r

n.r

Vorvida [33]

608

306

302

183 (30.0%)

114

69

183 (30.1%)

114

69

Zanadio [34]

149

n.r

n.r

10 (6.7%)

n.r

n.r

n.r

n.r

n.r