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Table 2 Study characteristics, interventions and comparators

From: The effectiveness of clinical guideline implementation strategies in oncology—a systematic review

Study (Reference)

Trial identifier

Country

Study design

Study period

Setting

Clinical Practice Guideline(s)

Interventiona

Comparator

Brown 2018

[38]

ACTRN12611001251910

Australia

stepped-wedge

cluster RCT

(9 clusters)

13.12.2013

-

27.08.2014

inpatient

Australian Guideline for the Management of Prostate Cancer (2010), American Urological Association Guideline (2013)

Multi-component

(opinion leaders, educational meetings and materials, audit and feedback, tailored intervention)

No intervention

Gilbert 2021

[37]

NCT0208452

France

stepped-wedge

cluster RCT

(5 clusters)

10.2013

-

12.2016

inpatient

ESPEN Guidelines on Nutrition in Cancer Patients

(2017)

Multi-component

(educational meetings and materials, academic detailing)

No intervention

Lovell 2022

[34]

ACTRN12615000064505

Australia

stepped-wedge

cluster RCT

(6 clusters)

08.2015

-

05.2019

outpatient

Cancer Council Australia Cancer pain management in adults (2020)

Multi-component

(opinion leaders, educational meetings and materials, audit and feedback)

No intervention

McCarter 2018

[35]

ACTRN12613000320752

Australia

stepped-wedge

cluster RCT

(5 clusters)

01.07.2013

-

27.03.2015

inpatient

National Comprehensive Cancer Network (NCCN)- Guidelines in Oncology, Head and Neck Cancers (2017)

Multi-component

(opinion leaders, educational meetings and materials, audit and feedback, academic detailing)

No intervention

Mohile 2021

[36]

NCT02054741

USA

Cluster RCT

29.07.2014

-

13.03.2019

inpatient

ASCO Guideline for Geriatric Oncology (2018)

Multi-component

(educational meetings and materials)

No intervention

Bonkowski 2018

[40]

NR

USA

Controlled before-and after study

NR

inpatient

Guidelines on the Management of Postoperative Pain (2016)

Multi-component

(educational meetings, educational materials, tailored intervention)

No intervention

Cowperthwaite 2019

[42]

NR

USA

Controlled before and after study

07.07.2017

30.11.2017

inpatient

National Comprehensive Cancer Network (NCCN)- CPG in Oncology, Adult Cancer Pain (2018)

Multi-component

(educational meetings, educational materials, patient-mediated intervention)

No intervention

Knoerl 2021

[41]

NCT03514680

USA

Controlled before-and after study

05.2018

11.2019

outpatient

American Society of Clinical Oncology (ASCO)-CPG for prevention and management of CIPN in survivors of adult cancers (2020)

Multi-component

(educational meetings, educational materials)

No intervention

Phillips 2017

[39]

NR

Australia

Controlled before-and after study

NR

(41 weeks)

inpatient

Australian Adult Cancer Pain Management Working Group- Cancer pain management in adults (2013)

Multi-component

(educational meetings, educational materials, audit and feedback)

No intervention

  1. NR Not reported, CIPN Chemotherapy-induced peripheral neuropathy, RCT Randomized controlled trial
  2. aClassification according to EPOC taxonomy [56]; tailored intervention = based on an assessment of barriers to change, for example through interviews or surveys; patient-mediated intervention = any intervention aimed at changing the performance of healthcare professionals through interactions with patients, or information provided by or to patients