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Table 1 PICO framework

From: The effectiveness of clinical guideline implementation strategies in oncology—a systematic review

P

I

C

O

Population

Intervention

Comparison

Outcome

Healthcare professionals (physicians, nurses, etc.)

CPG implementation of single or multi-component interventionsa in the oncological setting or any clinical setting related to oncology

No intervention (usual care), another single-component intervention or multi-component intervention

Primary (patient-level): Overall survival, Quality of Life, Adverse event(s)

Secondary (provider-level): Guideline adherence outcomesb

  1. CPG Clinical practice guideline
  2. asingle intervention = single-component or single strategy interventions (e.g. reminders only), multi-component intervention = intervention with two or more components or strategies (e.g. reminders combined with audit and feedback)
  3. bdefined as screening rate, referral, prescribing behaviour, knowledge, attitudes of healthcare professionals