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Table 1 Study characteristics

From: Cost-effectiveness of pegfilgrastim versus filgrastim for prevention of chemotherapy-induced febrile neutropenia in patients with lymphoma: a systematic review

Authors/year

Country

Perspective

Types of EE

Model type

Study population

Interventiona

Comparator

Type of prophylaxis

Fust et al. 2017 [23]

Belgium

Healthcare payer

CEA and CUA

Markov

205 elderly patients with aggressive NHL

Pegfilgrastim

6 and 11 days of filgrastim

Primary and secondary

Ravangard et al.2017 [33]

Iran

Healthcare payer

CEA

Decision tree

131 patients with relapsed NHL, aged 19–72

Pegfilgrastim

1 and 3 days of filgrastim

Primary

Wang et al. 2016 [24]

Singapore

Hospital

CEA and CUA

Markov

Hypothetical cohort of 55-year-old patients with NHL

Pegfilgrastim

7 days of biosimilar filgrastim

Primary and secondary

Lathia et al. 2013 [19]

Canada

Healthcare payer

CUA

Markov

Hypothetical cohort of 64-year-old patients with DLBCL

Pegfilgrastim

10 days of filgrastim

Primary

Perrier et al.2013 [32]

France

Hospital

CEA

Not specified

151 patients > 18 years with confirmed lymphoma

Pegfilgrastim

Average 6 days of filgrastim

Primary

Sebban et al.2012 [31]

France

Hospital

CEA

Not specified

151 patients > 18 years with confirmed lymphoma

Pegfligrastim

Average 6 days of filgrastim

Primary

Whyte et al. 2011 [21]

UK

Healthcare payer

CUA

Mathematical

Hypothetical patients age of 63 years with aggressive NHL

Pegfilgrastim

6 and 11 days of filgrastim

Primary and secondary

Lyman et al. 2009 [22]

USA

Healthcare payer

CEA and CUA

Decision tree

Hypothetical cohort of 65-year-old patients with intermediate- or high-grade NHL

Pegfilgrastim

6 days of filgrastim

Primary

  1. aPegfilgrastim was given per cycle of chemotherapy
  2. FN Febrile neutropenia, EE Economic Evaluation, DLBCL Diffuse large B-cell lymphomas, CEA cost-effectiveness analysis, CUA Cost-utility analysis, NHS National Health Service, USA United State of America, UK United Kingdom, NHL Non-Hodgkin lymphoma