Table 2 Trends in breast cancer screening and its direct costs in the target population and chemotherapy costs in localized and advanced disease from January 2017 to June 2021 in the public healthcare system in Brazil
Interrupted time series | The monthly trend of mammogram rate per 10,000 women aged 50 to 69 | The monthly trend of total direct costs of mammograms in women aged 50 to 69 | The monthly trend in the total direct cost of chemotherapy in localized disease (Stage I and II) | The monthly trend in the total direct cost of chemotherapy in advanced disease (Stages III and IV) | |
|---|---|---|---|---|---|
Segment 1 | Lower Endpoint | January 2017 | January 2017 | January 2017 | January 2017 |
Upper Endpoint | February 2020 | February 2020 | June 2020 | June 2020 | |
MPC | 0.0 | 0.1 | 0.2* | 0.6* | |
CI 95% | -0.4; 0.4 | −0.3; 0.5 | 0.2; 0.3 | 0.6, 0.6 | |
p value | 0.961 | 0.76 | < 0.001 | < 0.001 | |
Trend | stationary | stationary | increasing | increasing | |
Segment 2 | Lower Endpoint | March 2020** | March 2020** | July 2020 | |
Upper Endpoint | May 2020 | May 2020 | June 2021 | ||
MPC | −48.9* | − 45.5 | −0.4* | ||
CI 95% | −64.2; −27.2 | −73.1; 10.3 | − 0.7; − 0.1 | ||
p value | < 0.001 | 0.09 | <0.001 | ||
Trend | decreasing | stationary | decreasing | ||
Segment 3 | Lower Endpoint | June 2020 | June 2020 | ||
Upper Endpoint | October 2020 | November 2020 | |||
MPC | 44.6* | 33.3* | |||
CI 95% | 29.2; 61.8 | 17.2; 51.7 | |||
p value | < 0.001 | <0.001 | |||
Trend | increasing | increasing | |||
Segment 4 | Lower Endpoint | November 2020 | December 2020 | ||
Upper Endpoint | June 2021 | June 2021 | |||
MPC | −4.3* | −6.7* | |||
CI 95% | −7.9; −0.5 | −12.0; −1.0 | |||
p value | 0.027 | 0.022 | |||
Trend | decreasing | decreasing | |||
Total Time Series | MPC | −1.5* | −0.9* | 0.1* | 0.6* |
CI 95% | −2.2; −0.7 | − 1.3; − 0.4 | 0.1; 0.2 | 0.6; 0.6 | |
p value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |
Trend | decreasing | decreasing | increasing | increasing | |