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Table 5 Results of GLMs to assess the effects of patient characteristics on the total cost of AEs

From: Costs associated with adverse events from remission induction for children with Acute Lymphoblastic Leukemia (ALL)

Covariates

Coefficients

Estimates (USD)

p-value

95% confidence intervals (USD)

GLM 1

 Adverse events (0 = absent, 1 = present)

0.467

$3,750.06

0.013a

$802.89

$6,697.22

 Sex (0 = male, 1 = female)

0.160

$1,289.68

0.263a

-$966.69

$3,546.06

 Age (years)

0.002

$12.95

0.938a

-$313.52

$339.43

 Risk of neoplastic relapse (0 = standard, 1 = high)

0.302

$2,430.59

0.043a

$80.94

$4,780.24

 Time to get ALL remission (days)

0.041

$330.50

0.004a

$105.31

$555.69

 Hospitalization (0 = no, 1 = yes)

0.448

$3,601.37

0.002a

$1,302.69

$5,900.04

 Deaths

0.780

$6,273.87

0.028a

$693.88

$11,853.87

 Intercept

6.859

 

0.000a

  

GLM 2

 Adverse events (count predictor)

0.072

$564.64

0.002a

$202.07

$927.22

 Sex (0 = male, 1 = female)

0.042

$330.42

0.717a

-$1,453.15

$2,113.99

 Age (years)

0.005

$40.83

0.746a

-$206.29

$287.95

 Risk of neoplastic relapse (0 = standard, 1 = high)

0.259

$2,020.45

0.048a

$18.96

$4,021.94

 Hospitalization (0 = no, 1 = yes)

0.303

$2,364.41

0.028a

$250.26

$4,478.56

 Time to get ALL remission (days)

0.029

$226.73

0.002a

$80.36

$373.11

 Deaths

-0.169

-$1,320.33

0.656a

-$7,125.56

$4,484.90

 Intercept

7.383

 

0.000a

  
  1. GLM Generalized linear models, USD United States Dollar
  2. aWilcoxon rank sum test