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Table 4 Overall healthcare resource costs and per patient during the index year

From: Healthcare resource utilization and costs among patients with heart failure with preserved, mildly reduced, and reduced ejection fraction in Spain

 

All HF patients (N = 21,297)

All HFrEF (N = 10,323)

All HFmrEF (N = 903)

All HFpEF (N = 8225)

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

P vs HFrEF

n

Total cost (€)

€1

€2

P vs HFrEF

Outpatient

21,297

7.938.396,6

372.7 (196)

372.9 (196)

10,323

5.268.083,97

510.3 (174)

510.3 (174)

903

235.708,44

261 (108.1)

261.3 (107.8)

 < 0.001

8225

1.968.105,33

239.3 (108.1)

239.5 (107.9)

 < 0.001

 GPs visitsa

21,297

6.637.604,1

311.7 (175.1)

312.2 (174.7)

10,323

4.423.793,97

428.5 (170.4)

428.6 (170.4)

903

196.558,44

217.7 (85.2)

218.6 (84.1)

 < 0.001

8225

1.622.302,83

197.2 (85.7)

198 (85)

 < 0.001

 Specialist visitsa

21,297

1.300.792,5

61.1 (73.7)

122.8 (57.8)

10,323

844.290,00

81.8 (74.2)

120 (59.1)

903

39.150,00

43.4 (69)

129.2 (55.4)

 < 0.001

8225

345.802,50

42 (68.1)

129.2 (54.7)

 < 0.001

Inpatient

 Hospitalizations (> 24 hs)b

21,297

41.808.135,6

1963.1 (4311.6)

6285 (5688.3)

10,323

28.845.380,10

2794.3 (5419.3)

7999.3 (6514.7)

903

1.401.691,20

1552.3 (3356.8)

5191.4 (4338.4)

 < 0.001

8225

9.722.949,10

1182.1 (2705.2)

4336.7 (3628.9)

 < 0.001

Pharmacy

 Prescriptionsc

21,297

12.528.920,7

588.3 (206.3)

588.3 (206.3)

10,323

6.456.456,17

625.4 (204.8)

625.4 (204.8)

903

470.263,00

520.8 (186.3)

520.8 (186.3)

 < 0.001

8225

4.516.345,35

549.1 (201.2)

549.1 (201.2)

 < 0.001

Indirect cost

 Cost of absence from workd

21,297

5.730.105,4

269.1 (749.7)

1803.1 (1000.5)

10,323

4.425.103,62

428.7 (983.5)

2200.4 (1032.8)

903

109.003,17

120.7 (373.1)

1172.1 (345.3)

 < 0.001

8225

951.171,58

115.6 (357.2)

1092 (372.6)

 < 0.001

Total Overall cost

 

68.005.558,3

3193.2 (4457.7)

  

44.995.023,9

4358.7 (5522.8)

  

2.216.665,8

2454.8 (3391.2)

 

 < 0.001

 

17.158.571,4

2086.1 (2737.8)

 

 < 0.001

 

All HFpEF (50 to < 60%) (N = 2995)

All HFpEF (≥ 60%) (N = 5230)

All HFuEF (N = 1846)

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

n

Total cost (€)

€1

€2

Outpatient

2995

717.578,67

239.6 (108)

239.8 (107.8)

5230

1.250.526,66

239.1 (108.1)

239.2 (108)

1846

466.498,89

252.7 (103.5)

252.7 (103.5)

 GPs visitsa

2995

594.661,17

198.6 (85.6)

199.3 (84.9)

5230

1.027.641,66

196.5 (85.8)

197.3 (85)

1846

394.948,89

213.9 (79.3)

214.1 (79.2)

 Specialist visitsa

2995

122.917,50

41 (68.1)

131.2 (54.8)

5230

222.885,00

42.6 (68.1)

128.1 (54.6)

1846

71.550,00

38.8 (65.3)

124 (55.4)

Inpatient

 Hospitalizations (> 24 hs)b

2995

3.507.116,10

1171 (2688.2)

4308.5 (3616.4)

5230

6.215.833,00

1188.5 (2715.1)

4352.8 (3637.3)

1846

1.838.115,20

995.7 (2131.2)

3442.2 (2699.1)

Pharmacy

 Prescriptionsc

2995

1.642.571,36

548.4 (201.4)

548.4 (201.4)

5230

2.873.773,99

549.5 (201.1)

549.5 (201.1)

1846

1.085.856,22

588.2 (206.4)

588.2 (206.4)

Indirect cost

 Cost of absence from workd

2995

352.716,85

117.8 (359.8)

1098.8 (360.4)

5230

598.454,73

114.4 (355.8)

1088.1 (379.8)

1846

244.826,99

132.6 (403.4)

1206 (430.1)

Total Overall cost

 

6.219.983,0

2076.8 (2731.1)

  

10.938.588,4

2091.5 (2741.9)

  

3.635.297,3

1969.3 (2203.8)

 
  1. aCost was calculated based on standard cost for GP/ specialist visits
  2. bCost of inpatient stays was calculated based on the DRG-based reimbursement of the stays
  3. cCost was based on full price of product
  4. dCost of absence from work was calculated by multiplying the number of days of absence from work due to sickness by the mean daily salary of a working person
  5. All cost were presented in euros
  6. €1 mean cost per patient (SD) accounting for all patients, €2 mean cost per patient (SD) accounting for patients with ≥ 1 resource use, GP General practitioner, HF Heart failure, HFmrEF Heart failure with mildly reduced ejection fraction, HFpEF Heart Failure with preserved ejection fraction, HFrEF Heart failure with reduced ejection fraction, HFuEF Heart Failure with unspecified ejection, HRCU Healthcare resource utilization, n number of patients, SD Standard deviation
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