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Table 1 Clinical input data used in model

From: Cost analysis of lurasidone for the treatment of schizophrenia in adolescents and adults within the United Kingdom

Antipsychotic

Six-weekly

Discontinuation

Relapse

 ≥ 7% weight gain

EPS

Adverse events

Other reasons

Lurasidone: adolescents (80 mg)

1.3% [15]

8.8% [15]

2.1% [17]

5.9% [18]

28.7% [18]

Haloperidol (3 mg)

8.0% [19]

7.5% [18]

4.9% [20]

9.7% [18]

46.2% [18]

Paliperidone (6 mg)

3.4% [15]

3.8% [15]

1.9% [17]

14.7% [18]

23.8% [18]

Aripiprazole (10 mg)

15.3% [15]

25.7% [15]

4.6% [17]

9.0% [18]

19.5% [18]

Lurasidone: adults (148 mg)

7.6% [16]

18.2% [16]

2.1% [17]

5.9% [18]

28.7% [18]

Brexpiprazole (4 mg)

5.6% [16]

25.6% [16]

2.5% [17]

13.5% [18]

23.7% [18]

Cariprazine (6 mg)

8.5% [16]

28.8% [16]

3.7% [17]

5.6% [18]

32.7% [18]

Clozapine

NA

5.4% [18]

4.9% [21]

33.3% [22]

6.8% [18]

No treatment

NA

NA

7.1% [17]

NA

NA