Variable | Category | Reference Population | Hospitalisation | Death | ||||||
---|---|---|---|---|---|---|---|---|---|---|
No | Yes | OR (95% CI) | P>𝛘2 | No | Yes | HR (95% CI) | P>𝛘2 | |||
N | N.Obs | 536 (100.0) | 171 (31.9) | 365 (68.1) | 400 (74.6) | 136 (25.4) | ||||
Ageb | Continuous | 63.2 (19.1) | 50.4 (17.7) | 69.2 (16.7) | 1.06 (1.05–1.08) | < 0.001 | 57.4 (17.2) | 80.4 (13.2) | 1.08 (1.06–1.09) | < 0.001 |
Gender | Female | 264 (49.3) | 99 (57.9) | 165 (45.2) | 1.00 (−) | – | 201 (50.2) | 63 (46.3) | 1.00 (−) | – |
Male | 272 (50.7) | 72 (42.1) | 200 (54.8) | 1.67 (1.15–2.41) | < 0.01 | 199 (49.8) | 73 (53.7) | 1.12 (0.80–1.57) | 0.516 | |
Diabetes | No | 449 (83.8) | 164 (95.9) | 285 (78.1) | 1.00 (−) | – | 348 (87.0) | 101 (74.3) | 1.00 (−) | – |
Yes | 86 (16.0) | 7 (4.1) | 79 (21.6) | 6.49 (2.93–14.40) | < 0.001 | 52 (13.0) | 34 (25.0) | 1.87 (1.27–2.76) | < 0.01 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
CVD | No | 396 (73.9) | 148 (86.5) | 248 (67.9) | 1.00 (−) | – | 329 (82.2) | 67 (49.3) | 1.00 (−) | – |
Yes | 139 (25.9) | 23 (13.5) | 116 (31.8) | 3.01 (1.84–4.92) | < 0.001 | 71 (17.8) | 68 (50.0) | 3.50 (2.49–4.90) | < 0.001 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
Obesity | No | 479 (89.4) | 167 (97.7) | 312 (85.5) | 1.00 (−) | – | 361 (90.2) | 118 (86.8) | 1.00 (−) | – |
Yes | 27 (5.0) | 1 (0.6) | 26 (7.1) | 13.92 (1.87–103.47) | < 0.001 | 21 (5.2) | 6 (4.4) | 0.92 (0.40–2.08) | 0.830 | |
Missing | 30 (5.6) | 3 (1.8) | 27 (7.4) | – | – | 18 (4.5) | 12 (8.8) | – | – | |
Cancer | No | 490 (91.4) | 164 (95.9) | 326 (89.3) | 1.00 (−) | – | 369 (92.2) | 121 (89.0) | 1.00 (−) | – |
Yes | 46 (9.6) | 7 (4.1) | 39 (10.7) | 2.80 (1.23–6.40) | < 0.001 | 31 (7.8) | 15 (11.0) | 1.41 (0.83–2.41) | 0.228 | |
ESRD | No | 509 (95.0) | 170 (99.4) | 339 (92.9) | 1.00 (−) | – | 394 (98.5) | 115 (84.6) | 1.00 (−) | |
Yes | 26 (4.8) | 1 (0.6) | 25 (6.8) | 12.54 (1.68–93.31) | < 0.001 | 6 (1.5) | 20 (14.7) | 5.17 (3.21–8.34) | < 0.001 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
COPD | No | 490 (91.4) | 166 (97.1) | 324 (88.8) | 1.00 (−) | – | 379 (94.8) | 111 (81.6) | 1.00 (−) | – |
Yes | 46 (8.6) | 5 (2.9) | 41 (11.2) | 4.20 (1.63–10.83) | < 0.001 | 21 (5.2) | 25 (18.4) | 3.02 (1.95–4.66) | < 0.001 | |
Hypertension | No | 341 (63.6) | 146 (85.4) | 195 (53.4) | 1.00 (−) | – | 277 (69.2) | 64 (47.1) | 1.00 (−) | |
Yes | 194 (36.2) | 25 (14.6) | 169 (46.3) | 5.06 (3.16–8.11) | < 0.001 | 123 (30.8) | 71 (52.2) | 2.08 (1.48–2.91) | < 0.001 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
Fever | No | 108 (62.1) | 56 (32.7) | 52 (14.2) | 1.00 (−) | – | 77 (19.2) | 31 (22.8) | 1.00 (−) | – |
Yes | 428 (79.9) | 115 (67.3) | 313 (85.8) | 2.93 (1.90–4.52) | < 0.001 | 323 (80.8) | 105 (77.2) | 0.79 (0.53–1.18) | 0.252 | |
Cough | No | 279 (52.0) | 99 (57.9) | 180 (49.3) | 1.00 (−) | – | 193 (48.2) | 86 (63.2) | 1.00 (−) | |
Yes | 234 (43.7) | 69 (40.4) | 165 (45.2) | 1.32 (0.91–1.91) | 0.149 | 190 (47.5) | 44 (32.4) | 0.53 (0.37–0.76) | < 0.001 | |
Missing | 23 (4.3) | 3 (1.8) | 20 (5.5) | – | – | 17 (4.2) | 6 (4.4) | – | – | |
Asthenia | No | 391 (73.0) | 125 (73.1) | 266 (72.9) | 1.00 (−) | – | 280 (70.0) | 111 (81.6) | 1.00 (−) | |
Yes | 95 (17.7) | 30 (17.5) | 65 (17.8) | 1.02 (0.63–1.65) | 0.942 | 81 (20.2) | 14 (10.3) | 0.47 (0.27–0.82) | < 0.01 | |
Missing | 50 (9.3) | 16 (9.4) | 34 (9.3) | – | – | 39 (9.8) | 11 (8.1) | – | – | |
Diarrhea | No | 68 (12.7) | 32 (18.7) | 36 (9.9) | 1.00 (−) | – | 336 (84.0) | 131 (96.3) | 1.00 (−) | |
Yes | 467 (87.1) | 139 (81.3) | 328 (89.9) | 0.48 (0.28–0.80) | < 0.01 | 64 (16.0) | 4 (2.9) | 0.20 (0.07–0.54) | < 0.001 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
Dyspnea | No | 303 (56.5) | 136 (79.5) | 167 (45.8) | 1.00 (−) | – | 254 (63.5) | 49 (36.0) | 1.00 (−) | |
Yes | 232 (43.3) | 35 (20.5) | 197 (54.0) | 4.58 (3.00–7.01) | < 0.001 | 146 (36.5) | 86 (63.2) | 2.55 (1.80–3.62) | < 0.001 | |
Missing | 1 (0.2) | – | 1 (0.3) | – | – | – | 1 (0.7) | – | – | |
Procalcitonin ng/mL | < 0.2 | 370 (69.0) | 155 (90.6) | 215 (58.9) | 1.00 (−) | – | 325 (81.2) | 45 (33.1) | 1.00 (−) | |
≥0.2 | 159 (29.7) | 9 (5.3) | 150 (41.1) | 12.02 (5.95–24.28) | < 0.001 | 68 (17.0) | 91 (66.9) | 6.30 (4.40–9.02) | < 0.001 | |
Missing | 7 (1.3) | 7 (4.1) | – | – | – | 7 (1.8) | 0 (0.0) | – | – | |
LDH U/L | Low | 315 (58.8) | 51 (29.8) | 264 (72.3) | 1.00 (−) | – | 245 (61.3) | 46 (33.8) | 1.00 (−) | – |
High | 214 (41.2) | 113 (66.1) | 101 (27.7) | 5.79 (3.87–8.66) | < 0.001 | 148 (37.0) | 90 (66.2) | 2.56 (1.80–3.66) | < 0.001 | |
Missing | – | 7 (4.1) | – | – | – | 7 (1.8) | – | – | – | |
MDW | Low | 381 (71.1) | 72 (42.1) | 309 (84.7) | 1.00 (−) | – | 266 (66.5) | 65 (47.8) | 1.00 (−) | – |
High | 151 (28.2) | 98 (57.3) | 53 (14.5) | 7.94 (5.21–12.09) | < 0.001 | 132 (33.0) | 69 (50.7) | 1.76 (1.25–2.47) | < 0.01 | |
Missing | 4 (0.7) | 1 (0.6) | 3 (0.8) | – | – | 2 (0.5) | 2 (1.5) | – | – | |
Saturation % | High | 284 (53.0) | 148 (86.5) | 136 (37.3) | 1.00 (−) | – | 255 (63.7) | 29 (21.3) | 1.00 (−) | |
Low | 247 (46.1) | 21 (12.3) | 226 (61.9) | 11.71 (7.07–19.39) | < 0.001 | 141 (35.2) | 106 (77.9) | 4.83 (3.20–7.28) | < 0.001 | |
Missing | 5 (0.9) | 2 (1.2) | 3 (0.8) | – | – | 4 (1.0) | 1 (0.7) | – | – | |
D-dimer mg/L | Low | 289 (53.9) | 36 (21.1) | 253 (69.3) | 1.00 (−) | – | 282 (70.5) | 35 (25.7) | 1.00 (−) | – |
High | 232 (43.3) | 121 (70.8) | 111 (30.4) | 7.66 (4.96–11.82) | < 0.001 | 104 (26.0) | 100 (73.5) | 5.71 (3.88–8.39) | < 0.001 | |
Missing | 15 (2.8) | 14 (8.2) | 1 (0.3) | – | – | 14 (3.5) | 1 (0.7) | – | – | |
Prothrombin Time % | High | 165 (30.8) | 87 (50.9) | 78 (21.4) | 1.00 (−) | – | 324 (81.0) | 86 (63.2) | 1.00 (−) | – |
Low | 367 (68.5) | 80 (46.8) | 287 (78.6) | 4.00 (2.70–5.93) | < 0.001 | 72 (18.0) | 50 (36.8) | 2.17 (1.53–3.07) | < 0.001 | |
Missing | 4 (0.7) | 4 (2.3) | 0 (0.0) | – | – | 4 (1.0) | 0 (0.0) | – | – | |
CRP mg/L | Low | 336 (62.7) | 40 (23.4) | 296 (81.1) | 1.00 (−) | – | 237 (59.2) | 33 (24.3) | 1.00 (−) | – |
High | 200 (37.3) | 131 (76.6) | 69 (18.9) | 14.05 (9.04–21.82) | < 0.001 | 163 (40.8) | 103 (75.7) | 3.64 (2.46–5.40) | < 0.001 | |
Lymphocytes x103μL | High | 297 (55.4) | 137 (80.1) | 160 (43.8) | 1.00 (−) | – | 313 (78.2) | 70 (51.5) | 1.00 (−) | |
Low | 239 (44.6) | 34 (19.9) | 205 (56.2) | 5.16 (3.36–7.93) | < 0.001 | 87 (21.8) | 66 (48.5) | 2.71 (1.93–3.79) | < 0.001 |