Table 3 Model cost parameters presented in 2018 RMB
Parameters | Mean | Reference | ||
|---|---|---|---|---|
Screening by IF for PKU(per newborn) | 23 | Field investigation | ||
Screening by IF for CH(per newborn) | 23 | Field investigation | ||
Screening by IF for CAH(per newborn) | 23 | Field investigation | ||
Screening by IF for G6PD(per newborn) | 23 | Field investigation | ||
Screening by MS/MS (per newborn) | 296 | Field investigation | ||
Confirmation by IF (per newborn) | 319 | Field investigation | ||
Confirmation by MS/MS (per newborn) | 296 | Field investigation | ||
Treatment for the diseases (per person-year)a | Age groupsb | 0 ~ 5 years | 6 ~ 82 years | Guidelines for the Treatment of Rare Diseases (2019) [64] |
MSUD | 13,440.90 | 6083.00 | ||
HCY | 13,772.13 | 5952.51 | ||
CIT I、CIT II | 48,202.46 | 20,833.77 | ||
IVA | 17,567.81 | 13,045.01 | ||
GA I | 17,567.81 | 13,045.01 | ||
MMA | 19,023.76 | 24,692.53 | ||
PA | 17,567.81 | 19,839.39 | ||
MCAD, PCD, VLCAD | 15,853.26 | 15,853.26 | ||
PKU | 15,000.00 | 15,000.00 | Field investigation | |
Treatment for sequelae (per person-year)c | DD | 3,064 | [65] | |
ND | 53,400 | [66] | ||
MR | 12,000 | [67] | ||
RD | 70,213 | [68] | ||
Follow-up (per person-year) | IF (4 times) | 1,276 | Field investigation | |
MS/MS(4 times) | 1,184 | Field investigation | ||
Transportation (per year) | 435 | Field investigation | ||
Lost productivity (per year) | 3,060 | [69] | ||
Program cost | Sample transportation (per year) | 42,000 | Field investigation | |
Printing (per year) | 340,000 | |||
Cold-chain logistics (per year) | 470,000 | |||
Software development and maintenance, equipment updating, etc (per year) | 370,000 | |||
Utilities (per person-year) | 2.52 | [70], supposing 200,000 people are screened | ||
Administrative management (per person-year) | 1.81 | |||
Depreciation of buildings, equipment, etc | Sunk costs | |||