Defining optimal implementation packages for delivering community-wide mass drug administration for soil-transmitted helminths with high coverage

Table 1 Description and calibration of CNA variables

Outcome/Condition	Description	Factor	Calibration
High coverage of community-wide MDA	> 90% (per-protocol) ¹	COVERAGE	0 < 90% coverage 1 > 90% coverage
Drug supply chain	Timing of when albendazole arrive in each cluster	DRUG	0 Late arrival of albendazole (on first day of MDA) 1 Early arrival of albendazole (at least one day before MDA)
Implementer training	Proportion of community drug distributors (CDDs) trained prior to MDA in cluster	TRAIN	0 Not all CDDs trained 1 All CDDs trained
Community sensitization type	Type of community sensitization activity conducted in cluster ²	MTG, PUBLIC, PRINT, DOOR, RADIO, TV, NEWSPAPER	0 Sensitization activity not conducted 1 Sensitization activity conducted
Intervention duration	Number of days of MDA delivery	MDADAYS⁴	0 MDA delivered in > 10 days 1 MDA delivered in <= 10 days
Implementation context	Presence of ongoing interventions or events in the community that may have negatively impacted MDA delivery or uptake	CONTEXT	0 Non-conducive implementation context (at least one ongoing community intervention or event) 1 Conducive implementation context (no community interventions or events)

¹Per-protocol coverage defined as: the percentage of censused and eligible individuals treated with a single dose of albendazole.
²Sensitization activities incudes: community meetings (MTG), public address announcements (PUBLIC), distribution of printed education materials e.g., posters and banners (PRINT), door-to-door sensitization (DOOR), or mass media (RADIO, TV, NEWSPAPER).
³Television (TV) and news (NEWSPAPER) were removed from final dataset due to limited variation across cases.
⁴CDDs who participated in DeWorm3 were given 10 days to deliver community-wide MDA.

ISSN: 1472-6963