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Table 3 Adherence factors to medication use according to healthcare professionals in this study

From: Healthcare professionals’ perceptions on barriers and facilitators to DMARD use in rheumatoid arthritis

Categories

Facilitators

Barriers

Patient-related

Self-managing medication regimen such as:

Embedding medication intake in daily routine;

Tapering/dosing/discontinuing temporarily;

Managing medication stock at home

Experiencing redefinition of identity

Personality traits such as openness and conscientiousness

Feeling resistance to become dependent on (lifelong) medication

Pursuing a solution-oriented approach

Denying the existence of condition

Pursuing discipline in medication taking

Experiencing inner conflict of medication necessity versus concerns

Coping with insecurity how future/condition will unfold, having a realistic expectation

Lacking confidence and/or not feeling safe enough to talk about e.g. (non) adherence

Maintaining autonomy and improving quality of life

Having trouble to understand instruction inserts

Being able to take care of family

Not believing in prescribed treatment, preferring traditional medication

Being able to open medication bottles/packages and administer injections/oral medications

Not believing that medication will always be available

Using aids to remember/motivate adherence

Not believing that condition needs (lifelong) medication

Believing in positive treatment effect

Believing that the condition can be cured

Experiencing positive emotions evoked by (positive experience of) medication

Attributing decreased treatment effect due to non-medical switch

 

Experiencing negative emotions that are evoked by using medication for a chronic condition

Therapy-related

Experiencing a short-term onset of medication effectiveness

Experiencing side effects

Experiencing positive treatment effect

Dreading possible interactions (medications, alcohol)

Employing a dose-reducing strategy

Being confronted with changed appearance of medication

Aligning patient preferences for medication administration

Perceiving information overload

 

Dealing with complexity of instruction inserts

Condition-related

Experiencing high level of disease activity

Perceiving treatment as redundant without a definite diagnosis

 

Experiencing a poor general health status e.g. suffering comorbidities (poly pharmacy)

Healthcare team and system-related

Providing tailored information frequently

Imposing limited consultation time to discuss choice of medication

Discussing reasons for non-adherence before and during therapy

Lacking reimbursement medication

HCPs are more accessible for patients (by different channels)

 

Offering optimal service logistics medication

 

Creating bond/empathy/trust with patient

 

Physician’s positive attitude on medication use

 

Initiating shared decision-making process by HCPs

 

Social and Economic

Receiving social and work-related support

Travelling

 

Nature of work hindering medication use (shifts)

 

Perceiving negative impact of social media/internet

 

Perceiving negative experiences/stories from others about medication

 

Interference in medication use because of religious or cultural customs