Economic impact of switching from partially combined vaccine “Pentaxim® and hepatitis B” to fully combined vaccine “Hexaxim®” in the Malaysian National Immunization Program

Table 3 Summary of cost borne by parents (direct non-medical and indirect cost) by immunization schemes

Comparison of cost saving (RM)	Perspective	Baseline scheme^a		Alternative scheme^b
Comparison of cost saving (RM)	Perspective	Pentaxim® + hepatitis B	Hexaxim®	Pentaxim® + hepatitis B	Hexaxim®
Cost per dose	Transportation	54.40	27.20	54.40	27.20
	Loss of productivity	221.33	110.66	221.33	110.66
	Total	275.73	137.86	275.73	137.86
Cost per FIC	Transportation	190.40	108.80	190.40	136.00
	Loss of productivity	774.64	442.65	774.64	553.31
	Total	965.04	551.45	965.04	689.31
	Saving	413.60		275.73
Cost per birth cohort (2019)^c	Transportation	92,980,317	53,131,610	92,980,317	66,414,512
	Loss of productivity	378,288,574	171,899,835	378,288,574	214,874,794
	Total	471,268,891	225,031,445	471,268,891	281,289,306
	Saving	246,237,446		189, 979,585
Cost savings per dose of Hexaxim®		126.06		97.26

Abbreviations: FIC fully immunized child, RM Malaysian ringgit
^aBased on four doses of Hexaxim®
^bPer four doses of Hexaxim® + one dose at birth for hepatitis B
^cBirth cohort (2019): 488,342 live birth according to the department of statistics Malaysia

ISSN: 1472-6963