Table 1 Breakdown of value areas into value objectives and activities, and key indicators identified at each level of the framework. Value areas were designed to reflect patient, healthcare provider, payer, and public health perspective. Objectives and activities were identified using a logframe approach. Indicators were identified following a Donabedian model. In the framework, outcome indicators are defined at the area and objective level, process indicators are defined at the activity level

Prevent New Infections

#

of new HIV infections

Rate

hiv incidence per 100 000 population

Provide and support combined prevention

PrEP

Ensure that people at risk of hiv acquisition have access to PrEP

#

of individuals who were newly enrolled on oral antiretroviral PrEP

#

of individuals, inclusive of those newly enrolled, that received oral antiretroviral PrEP

PEP

Provide access to PEP

#

of individuals who receive PEP

Prevent mother-to-child transmission

%

children newly infected with HIV from mother-to-child transmission

Provide ART to pregnant women living with hiv

%

Pregnant women with controlled VL

Provide education and increase awareness

To/in target populations (MSM, migrants, PWID, …)

Increase number of people informed about existing prevention measures towards HIV/STI

%

Target population informed on existing prevention measures towards HIV and STI

To/in the healthcare professionals

Ensure that all HCPs receive training on combination prevention tools

% and #

Of health care providers who receive training on combination prevention tools

Provide prevention services (condom use, counseling on risk reduction strategies, chemsex, hiv testing, …)

To/in target populations (MSM, migrants, PWID, …)

Increase number of people who receive prevention services

% and #

Of target population who receive prevention services

Improve the cascade of care

Rate

Number of people that have died from aids-related causes per 100 000 population

Reduce the number of undiagnosed patients

%

of undiagnosed PLWH

Provide (targeted) testing

#

of tests performed annually

Provide access to decentralized testing

Y/N

Availability of decentralised testing

Provide access to community testing

Y/ N

Availability of community testing

Aim for early diagnosis

% and #

of late diagnoses

Link diagnosed patients to care

%

of diagnosed PLWH linked to care

Quick follow-up by reference center

% and #

of newly diagnosed PLWH that are seen by hiv specialist within 2 weeks of diagnosis

Retain patients in care

%

of PLWH retained in care

Re-engage patients lost-to follow-up

% and #

of PLWH that were contacted after a standard defaulting period

% and #

of PLWH that were re-entered in care after a standard defaulting period

Regular follow-up of patients

% and #

of PLWH that have at least 1 follow-up visit in the reporting period

#

of multidisciplinary team meetings over the course of the reporting period

Achieve and maintain virologic control

%

of patients on ART with controlled viral load

Initiate ART treatment

% and #

of people on ART among PLWH

Follow-up ART treatment

%

of PLWH that have at least 1 measurement of VL in the reporting period

Follow-up ART treatment

%

of PLWH with abnormal VL that achieve controlled VL after follow-up

Provide Patient-Centered HIV Care

Support patient's quality of life

%

of PLWH with good QoL as measured by standardized tool

Measure at least once per year QoL

%

of patients in follow-up with QoL being measured each year

Provide at least once per year advice for mental wellbeing

# and %

of patients having received support/advice for mental wellbeing

Prevent and manage comorbidities

Rate

Incidence of specific comorbidities per 100 000 population

Prevention

Screening for hiv/treatment-related comorbidities

%

of PLWH being annualy screened for hiv/treatment related comorbidities

%

of PLWH with a smoking history documented in the last 2 years

%

of PLWH with blood pressure recorded in the last 15 months

Management

Follow-up management of comorbidities

# and %

of PLWH with known comorbidities

%

of PLWH with renal function being assessed annualy

Maintain sexual and reproductive health

Support sexual well-being & reduce risk behavior

Screening for risk behaviour

# and %

of patients in follow-up screened screened annually for risk behaviour

Regular asessment of sexual wellbeing

# and %

of patients in follow-up in which sexual wellbeing is assessed annually

Refer patients with risky behaviour referred to prevention services

# and %

of patients with risk behaviour referred to prevention services

Provide sexual wellbeing counseling

# and %

of patients in follow-up that received sexual wellbeing counseling

Manage and reduce hepatatis B and C infection in the hiv/aids population

Provide routine hepatitis B testing

%

of people starting ART who were tested for hepatitis B

Provide suitable combination therapy to hiv/hbv co-infected people

%

of people coinfected with hiv and hbv receiving combination treatment

Provide routine hepatitis C testing

%

of people starting ART who were tested for hepatitis C

Provide suitable combination therapy to hiv/hbc co-infected people

%

of people coinfected with hiv and hcv having received HCV treatment in the recorded year

Sustaining a state of the art disease management context

Support public health surveillance

Provide data for national reporting

%

Data completion

Improve knowledge through research and training

Provide training

Provide training

Training of future HCW (for ARCs associated with teaching institutions)

# and type

of training sessions

Support training of volunteers for demedicalized testing

[Y/N]

Availability of training protocol for training non-medical staff for demedicalized testing

#

Of accreditations awared for demedicalized training

Participate to training

Continuous (medical) education for the multidisciplinary ARC team

#

of training sessions to which members of the multidisciplinary ARC team assisted

Contribute / learn from scientific body of evidence

Contribute to scientific publications / research

#

of studies to which the reference center or its team members have contributed

#

or publications (peer-reviewed / gray)

Active participation to scientific events/meetings

#

of scientific meetings organized / participated to by the reference center or its team members

Support representative organizations

Organize / attend meetings with reprsensentative organizations

#

of meetings to which reference center team members have participated