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Table 2 Summary of the scores for the 16 criteria used to assess the methodological quality shown for all studies, quantitative and qualitative studies*

From: Barriers and facilitators to the uptake of new medicines into clinical practice: a systematic review

QASTDD tool criteria and study design

Range

Mean

Standard deviation

% maximum of possible score achieved

1. Explicit theoretical framework (all studies)

0–3

1.9

0.9

62%

Quantitative studies

0–3

1.9

0.9

62%

Qualitative studies

1–3

1.7

1.2

56%

2. Statement of aims/objectives in main body of report (all studies)

2–3

2.8

0.4

93%

Quantitative studies

2–3

2.8

0.4

92%

Qualitative studies

3

3

0

100%

3. Clear description of research setting (all studies)

2–3

2.7

0.5

89%

Quantitative studies

2–3

2.7

0.5

89%

Qualitative studies

2–3

2.7

0.5

89%

4. Evidence of sample size considered in terms of analysis (all studies)

0–3

1.5

0.7

50%

Quantitative studies

1–3

1.5

0.6

49%

Qualitative studies

0–3

2

1.7

67%

5. Representative sample of target group of a reasonable size (all studies)

1–3

2.2

0.5

74%

Quantitative studies

1–3

2.2

0.5

75%

Qualitative studies

2

2

0

67%

6. Description of procedure for data collection (all studies)

1–3

2.4

0.7

81%

Quantitative studies

1–3

2.4

0.7

81%

Qualitative studies

2–3

2.7

0.6

89%

7. Rationale for choice of data collection tool(s) (all studies)

0–3

1.7

0.9

58%

Quantitative studies

0–3

1.8

0.8

59%

Qualitative studies

0–2

0.7

1.2

22%

8. Detailed recruitment data (all studies)

0–3

2.0

1.0

67%

Quantitative studies

0–3

2.0

1.0

68%

Qualitative studies

0–3

1.7

1.5

56%

9. Statistical Assessment of reliability and validity of measurement tool(s) (Quantitative studies only)

0–3

0.9

1.1

29%

10. Fit between stated research question and method of data collection (Quantitative studies only)

2–3

2.8

0.4

93%

11. Fit between stated research question and format and content of data collection tool e.g. interview schedule (Qualitative studies only)

2–3

2.3

0.5

75%

12. Fit between research question and method analysis (all studies)

2–3

2.9

0.3

97%

Quantitative studies

2–3

2.9

0.2

98%

Qualitative studies

2–3

2.3

0.6

78%

13. Good justification for analytical method selected (all studies)

0–3

2.4

0.8

81%

Quantitative studies

0–3

2.5

0.8

83%

Qualitative studies

2–3

2.7

0.6

89%

14. Assessment of reliability of analytical process (Qualitative studies only)

0–2

1.0

0.8

33%

15. Evidence of user involvement in design (all studies)

0

0

0

0%

16. Strengths and limitations critically discussed (all studies)

0–3

1.9

0.7

63%

Quantitative studies

0–3

1.9

0.7

63%

Qualitative studies

1–2

1.3

0.6

44%

  1. *Quantitative studies n = 62, qualitative studies n = 3, mixed-methods study n = 1. As there was only one mixed-methods study, its scores were included in reporting score for all studies and individual scores can be found in Additional file 3, Table S1