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Table 3 Tendency of the time series analysis from the data regarding the hospitalizations and health care costs (total costs, hospital services and professional services), discriminated by immunopreventable disease and Brazil geographic areas, in the period from 2008 to 2018

From: Costs related to immunopreventable diseases: Brazil and its geographic areas (immunopreventable diseases’ costs in Brazil)

Immunopreventable disease by country areas

Hospitalizations

Total costs

 

Beta

P

CI95%

Tendency

Beta

P

CI95%

Tendency

Mumps (2008-2018)

BRAZIL

0.052

0.001

0.026

0.0776

Growing

0.067

0.000

0.046

0.088

Growing

  CENTER-WEST

0.043

0.023

0.007

0.079

Growing

0.067

0.006

0.025

0.110

Growing

  NORTHEAST

0.058

0.000

0.035

0.079

Growing

0.060

0.004

0.024

0.097

Growing

  NORTH

0.090

0.000

0.061

0.119

Growing

0.105

0.000

0.069

0.141

Growing

  SOUTHEAST

0.041

0.004

0.017

0.066

Growing

0.063

0.000

0.049

0.076

Growing

  SOUTH

0.061

0.007

0.021

0.100

Growing

0.065

0.001

0.032

0.099

Growing

Whooping cough (2008-2018)

BRAZIL

0.026

0.549

-0.070

0.124

Stationary

0.033

0.468

-0.065

0.132

Stationary

  CENTER-WEST

0.001

0.981

-0.107

0.109

Stationary

0.005

0.920

-0.106

0.116

Stationary

  NORTHEAST

0.061

0.229

-0.046

0.168

Stationary

0.070

0.209

-0.047

0.188

Stationary

  NORTH

0.038

0.378

-0.054

0.130

Stationary

0.041

0.297

-0.042

0.124

Stationary

  SOUTHEAST

0.022

0.610

-0.075

0.121

Stationary

0.030

0.506

-0.069

0.130

Stationary

  SOUTH

0.009

0.815

-0.083

0.103

Stationary

0.015

0.703

-0.074

0.105

Stationary

Diphtheria (2008-2018)

BRAZIL

-0.029

0.018

-0.052

-0.0064

Decreasing

-0.024

0.235

-0.066

0.018

Stationary

  CENTER-WEST

-0.072

0.058

-0.147

0.003

Stationary

-0.057

0.285

-0.170

0.056

Stationary

  NORTHEAST

-0.005

0.806

-0.054

0.043

Stationary

0.007

0.844

-0.078

0.093

Stationary

  NORTH

-0.054

0.180

-0.139

0.030

Stationary

-0.086

0.187

-0.223

0.050

Stationary

  SOUTHEAST

-0.039

0.001

-0.056

-0.021

Decreasing

-0.042

0.001

-0.064

-0.021

Decreasing

  SOUTH

-0.002

0.898

-0.052

0.046

Stationary

0.004

0.915

-0.081

0.090

Stationary

Meningococcal disease (2008-2018)

BRAZIL

-0.043

0.011

-0.074

-0.012

Decreasing

-0.028

0.124

-0.065

0.009

Stationary

  CENTER-WEST

-0.033

0.010

-0.056

-0.01

Decreasing

-0.029

0.094

-0.066

0.006

Stationary

  NORTHEAST

-0.030

0.096

-0.068

0.006

Stationary

-0.006

0.779

-0.060

0.046

Stationary

  NORTH

-0.018

0.007

-0.029

-0.006

Decreasing

-0.016

0.176

-0.041

0.009

Stationary

  SOUTHEAST

-0.055

0.012

-0.095

-0.015

Decreasing

-0.039

0.072

-0.083

0.004

Stationary

  SOUTH

-0.041

0.002

-0.062

-0.020

Decreasing

-0.029

0.004

-0.047

-0.012

Decreasing

Yellow fever (2008-2018)

BRAZIL

0.123

0.241

-0.099

0.346

Stationary

0.182

0.206

-0.120

0.484

Stationary

  CENTER-WEST

-0.027

0.258

-0.078

0.023

Stationary

-0.131

0.564

-0.629

0.366

Stationary

  NORTHEAST

0.031

0.467

-0.061

0.123

Stationary

0.010

0.840

-0.100

0.120

Stationary

  NORTH

-0.073

0.051

-0.147

0.000

Stationary

-0.025

0.569

-0.122

0.071

Stationary

  SOUTHEAST

0.168

0.183

-0.096

0.433

Stationary

0.258

0.120

-0.082

0.599

Stationary

  SOUTH

0.0008

0.985

-0.102

0.104

Stationary

0.0008

0.989

-0.134

0.135

Stationary

Influenza (2008-2018)

BRAZIL

-0.023

0.001

-0.034

-0.013

Decreasing

-0.019

0.014

-0.033

-0.0052

Decreasing

  CENTER-WEST

-0.077

0.002

-0.116

-0.037

Decreasing

-0.065

0.007

-0.106

-0.023

Decreasing

  NORTHEAST

-0.011

0.425

-0.043

0.020

Stationary

-0.004

0.801

-0.047

0.038

Stationary

  NORTH

-0.005

0.523

-0.026

0.014

Stationary

-0.003

0.778

-0.027

0.021

Stationary

  SOUTHEAST

-0.034

0.037

-0.066

-0.002

Decreasing

-0.026

0.124

-0.060

0.008

Stationary

  SOUTH

-0.026

0.014

-0.045

-0.006

Decreasing

-0.028

0.028

-0.053

-0.003

Decreasing

Hepatitis B (2008-2018)

BRAZIL

-0.041

0.006

-0.068

-0.014

Decreasing

-0.012

0.365

-0.043

0.017

Stationary

  CENTER-WEST

-0.026

0.078

-0.057

0.0037

Stationary

0.011

0.445

-0.021

0.045

Stationary

  NORTHEAST

-0.028

0.084

-0.061

0.0046

Stationary

-0.008

0.575

-0.041

0.024

Stationary

  NORTH

-0.055

0.038

-0.106

-0.0037

Decreasing

-0.035

0.112

-0.080

0.010

Stationary

  SOUTHEAST

-0.039

0.024

-0.072

-0.006

Decreasing

-0.009

0.658

-0.057

0.038

Stationary

  SOUTH

-0.061

0.005

-0.099

-0.024

Decreasing

-0.038

0.054

-0.077

0.0008

Stationary

Human rabies virus (2008-2018)

BRAZIL

-0.056

0.036

-0.107

-0.004

Stationary

-0.008

0.738

-0.066

0.049

Stationary

  CENTER-WEST

-0.064

0.055

-0.131

0.0018

Stationary

-0.200

0.187

-0.517

0.116

Stationary

  NORTHEAST

-0.085

0.010

-0.145

-0.025

Decreasing

-0.057

0.120

-0.133

0.018

Stationary

  NORTH

0.061

0.085

-0.010

0.134

Stationary

0.246

0.177

-0.133

0.626

Stationary

  SOUTHEAST

-0.067

0.332

-0.215

0.081

Stationary

-0.036

0.768

-0.305

0.233

Stationary

  SOUTH

-0.077

0.228

-0.212

0.057

Stationary

-0.102

0.516

-0.445

0.2400

Stationary

Rubella / German measles (2008-2018)

BRAZIL

-0.056

0.002

-0.086

-0.025

Decreasing

-0.049

0.217

-0.133

0.034

Stationary

  CENTER-WEST

-0.052

0.064

-0.109

0.0036

Stationary

-0.207

0.031

-0.391

-0.024

Decreasing

  NORTHEAST

-0.055

0.062

-0.114

0.0035

Stationary

-0.050

0.051

-0.100

0.0003

Stationary

  NORTH

-0.034

0.126

-0.080

0.0117

Stationary

-0.164

0.106

-0.372

0.043

Stationary

  SOUTHEAST

-0.069

0.003

-0.108

-0.029

Decreasing

-0.047

0.036

-0.091

-0.003

Decreasing

  SOUTH

-0.031

0.188

-0.081

0.018

Stationary

-0.029

0.296

-0.088

0.030

Stationary

Measles (2008-2018)

BRAZIL

0.035

0.342

-0.044

0.115

Stationary

0.039

0.126

-0.013

0.092

Stationary

  CENTER-WEST

-0.122

0.011

-0.208

-0.036

Decreasing

-0.132

0.270

-0.388

0.122

Stationary

  NORTHEAST

0.050

0.067

-0.004

0.104

Stationary

0.081

0.009

0.0264

0.136

Growing

  NORTH

0.020

0.515

-0.049

0.090

Stationary

-0.093

0.004

-0.146

-0.040

Decreasing

  SOUTHEAST

-0.028

0.364

-0.096

0.038

Stationary

-0.034

0.171

-0.086

0.017

Stationary

  SOUTH

-0.061

0.289

-0.185

0.062

Stationary

-0.063

0.369

-0.215

0.088

Stationary

Neonatal and accidental tetanus (2008-2018)

BRAZIL

-0.003

0.224

-0.009

0.002

Stationary

0.013

0.079

-0.0018

0.028

Stationary

  CENTER-WEST

0.0007

0.941

-0.019

0.021

Stationary

-0.008

0.697

-0.053

0.037

Stationary

  NORTHEAST

-0.006

0.599

-0.033

0.020

Stationary

0.014

0.127

-0.0051

0.035

Stationary

  NORTH

-0.008

0.446

-0.031

0.015

Stationary

0.031

0.225

-0.022

0.085

Stationary

  SOUTHEAST

0.006

0.444

-0.012

0.025

Stationary

0.014

0.344

-0.018

0.049

Stationary

  SOUTH

-0.003

0.765

-0.021

0.017

Stationary

0.009

0.102

-0.002

0.022

Stationary

Chickenpox/Herpes Zoster (2008-2018)

BRAZIL

-0.037

0.000

-0.045

-0.029

Decreasing

-0.021

0.012

-0.036

-0.006

Decreasing

  CENTER-WEST

-0.043

0.007

-0.071

-0.015

Decreasing

-0.030

0.107

-0.068

0.007

Stationary

  NORTHEAST

-0.011

0.016

-0.021

-0.002

Decreasing

0.022

0.000

0.015

0.028

Growing

  NORTH

-0.032

0.034

-0.061

-0.002

Decreasing

-0.056

0.010

-0.095

-0.017

Decreasing

  SOUTHEAST

-0.040

0.000

-0.049

-0.031

Decreasing

-0.025

0.032

-0.048

-0.002

Decreasing

  SOUTH

-0.049

0.008

-0.081

-0.016

Decreasing

-0.038

0.103

-0.087

0.009

Stationary

  1. Source: Unique Health System Information (DATASUS - TABNET). Period of the collected data from 2008 to 2018