Univariate - OR (CI) | Multivariate - OR (CI) | |||
---|---|---|---|---|
MDTM status | No | Unknown | No | Unknown |
Sex | p = 0.01 | p = 0.12 | p = 0.34 | p = 0.97 |
Male | 1 | 1 | 1 | 1 |
Female | 1.5 (1.1–2.0) | 1.2 (1.0–1.4) | 1.2 (0.8–1.7) | 1 (0.8–1.2) |
Age at diagnosis (years) | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 |
≤50 | 1 | 1 | 1 | 1 |
[51–65] | 1.1 (0.3–3.7) | 1.7 (0.9–3.2) | 1 (0.3–3.6) | 1.7 (0.9–3.3) |
[66–75] | 2.2 (0.7–7.2) | 2.8 (1.5–5.2) | 1.8 (0.5–6.3) | 2.5 (1.3–4.7) |
[76–80] | 3.6 (1.1–12.2) | 2.8 (1.5–5.4) | 2.3 (0.6–8.3) | 2.5 (1.2–4.8) |
> 80 | 9.3 (2.9–29.4) | 4.6 (2.5–8.4) | 3.8 (1.1–13) | 3.8 (2.0–7.2) |
Death within 3 months after diagnosis | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 |
No | 1 | 1 | 1 | 1 |
Yes | 15.4 (11–21.4) | 3.0 (2.3–4.0) | 12.1 (8.2–18) | 2.8 (2–3.9) |
Tumour localisation | p < 0.001 | p < 0.001 | p = 0.02 | p < 0.001 |
Colon | 1 | 1 | 1 | 1 |
Rectal | 0.5 (0.3–0.7) | 0.5 (0.4–0.6) | 0.6 (0.4–0.9) | 0.5 (0.4–0.6) |
Metastasis | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 |
Yes | 0.9 (0.7–1.3) | 0.7 (0.5–0.9) | 0.5 (0.3–0.8) | 0.5 (0.4–0.7) |
No | 1 | 1 | 1 | 1 |
Unknown | 11.6 (6.1–22) | 8 (4.9–13.3) | 4.5 (2–10) | 4 (2.2–7.1) |
Charlson Comorbidity Index | p < 0.001 | p < 0.001 | p = 0.08 | p < 0.001 |
0 | 1 | 1 | 1 | 1 |
1 | 2.5 (1.7–3.8) | 1.3 (1.0–1.7) | 1.7 (1.1–2.6) | 1.1 (0.8–1.5) |
> 1 | 3.1 (2.1–4.6) | 1.8 (1.4–2.3) | 1.7 (1.1–2.6) | 1.3 (1.0–1.7) |
Unknown | 1.7 (0.9–3.2) | 4.7 (3.6–6.1) | 1.5 (0.8–3.2) | 2.6 (2.0–3.6) |
Travel time quintiles (min) | p = 0.05 | p < 0.001 | p = 0.12 | p < 0.001 |
Q1 [3–10] | 1 | 1 | 1 | 1 |
Q2 [11–17] | 0.7 (0.4–1.2) | 1.5 (1.1–2.1) | 0.7 (0.4–1.2) | 1.8 (1.3–2.7) |
Q3 [18–28] | 1.3 (0.8–2.0) | 1.6 (1.1–2.2) | 1.2 (0.7–2.1) | 1.6 (1.1–2.3) |
Q4 [29–39] | 1.5 (0.9–2.3) | 2.0 (1.5–2.8) | 1.4 (0.8–2.3) | 2.4 (1.7–3.5) |
Q5 [40–75] | 1.3 (0.8–2.1) | 3.0 (2.2–4.1) | 1.3 (0.8–2.3) | 3.5 (2.5–4.9) |
European Deprivation Index quintiles | p = 0.47 | p = 0.22 | p = 0.55 | p = 0.72 |
Q1 (less deprived) | 1 | 1 | 1 | 1 |
Q2 | 1.1 (0.7–1.8) | 1.1 (0.8–1.5) | 0.9 (0.5–1.6) | 1.0 (0.7–1.4) |
Q3 | 1.5 (0.9–2.4) | 1.1 (0.8–1.4) | 1.1 (0.6–1.8) | 0.8 (0.6–1.2) |
Q4 | 1.1 (0.7–1.9) | 1.4 (1.0–1.8) | 0.7 (0.4–1.3) | 1.0 (0.7–1.4) |
Q5 (most deprived) | 1.2 (0.7–2.0) | 1.2 (0.9–1.7) | 0.8 (0.4–1.3) | 0.9 (0.6–1.3) |
Period | p < 0.001 | p < 0.001 | p < 0.001 | p < 0.001 |
[2005–2006] | 1 | 1 | 1 | 1 |
[2007–2009] | 1.0 (0.5–2.1) | 0.4 (0.3–0.5) | 0.8 (0.4–1.8) | 0.3 (0.3–0.4) |
[2010–1014] | 3.1 (1.7–5.7) | 0.1 (0.1–0.2] | 3.0 (1.6–5.6) | 0.1 (0.1–0.2] |