Scheme 1 | Scheme 2 |
---|---|
Indicated for: | Indicated for: |
Never-treated patients | Relapses and those who had previously discontinued treatment, then returned |
Medications: | Medications: |
Isoniazid (H), Rifampicin (R), Pyrazinamide (Z) and Ethambutol (E) - HRZE | Rifampicin (R), Isoniazid (H), Pyrazinamide (Z), Ethambutol (E) and Streptomycin (S) - RHZES |
Duration: | Duration: |
6 months, 82 doses | 8 months, 125 doses |
Phase 1: | Phase 1: |
50 doses (daily from Monday to Saturday) of HRZE | 75 doses (daily from Monday to Saturday) of RHZES then one month (daily Monday to Saturday) of RHZE |
Phase 2: | Phase 2: |
32 doses (twice a week) of RH | 40 doses (twice a week) of RHE |