Impact of weight trajectory after bariatric surgery on co-morbidity evolution and burden

Table 4 Proportional difference in total 10-year costs according to post-surgical weight loss trajectory improvement

Group	G1	G2	G3	G4	G5	G6
G1	0.0% [0.0, 0.0%]
G2	−11.0% [− 14.1, −8.8%]	0.0% [0.0, 0.0%]
G3	−22.2% [−28.0, − 18.3%]	−12.6% [− 16.3, − 10.3%]	0.0% [0.0, 0.0%]
G4	−35.3% [− 43.5, − 29.5%]	−27.3% [− 34.6, − 22.6%]	−16.8% [− 22.4, − 13.2%]	0.0% [0.0, 0.0%]
G5	−38.1% [−45.3, − 32.7%]	−30.5% [− 36.7, − 25.7%]	−20.5% [− 24.9, − 15.9%]	−3.8% [− 7.8, − 1.8%]	0.0% [0.0, 0.0%]
G6	−50.2% [− 59.9, − 41.2%]	−44.0% [− 53.7, − 34.9%]	−36.0% [− 45.6, − 26.6%]	−23.0% [− 31.4, − 15.2%]	−19.3% [− 28.6, − 12.3%]	0.0% [0.0, 0.0%]

Values shown indicate the percentage change in total 10-year costs for a cohort of 100 patients who experience improvement in weight loss trajectory (G1 poorest, G6 greatest weight loss). Starting trajectories are across the top and destination trajectories vertically. An extreme improvement of 100 patients from G1 to G6 is therefore estimated to be associated with a 50% reduction in costs of treatment of co-morbidities, while an intermediate improvement from G2 to G4 is estimated to be associated with 27% lower costs of co-morbidity treatment over 10 years. Co-morbidities are restricted to the three of the present study (type 2 diabetes mellitus, hypertension and dyslipidaemia)

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