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Table 3 Estimated additional cost of antibiotic use for URI in ambulatory care (unit = million USD)a

From: Cost of inappropriate antimicrobial use for upper respiratory infection in Japan

Age group (years)

2013

2014

2015

2016

0–4

40·3 (39·9–40·7)

32·7 (32·4–33·0)

27·2 (26·9–27·5)

22·1 (21·8–22·3)

5–9

56·6 (55·9–57·3)

50·1 (49·5–50·7)

51·1 (50·5–51·8)

43·4 (42·8–43·9)

10–14

31·2 (30·7–31·7)

27·7 (27·3–28·1)

29·0 (28·6–29·4)

24·4 (24·0–24·7)

15–19

19·5 (19·1–19·8)

14·6 (14·4–14·8)

16·1 (15·8–16·4)

14·0 (13·8–14·3)

20–24

17·2 (16·9–17·5)

11·4 (11·2–11·6)

11·1 (11·0–11·3)

9·5 (9·3–9·6)

25–29

22·4 (22·0–22·7)

16·1 (15·8–16·4)

15·5 (15·3–15·8)

12·6 (12·4–12·8)

30–34

31·2 (30·8–31·7)

23·9 (23·6–24·2)

23·9 (23·5–24·2)

19·8 (19·5–20·1)

35–39

38·0 (37·4–38·5)

29·9 (29·5–30·3)

29·6 (29·2–30·0)

23·7 (23·4–24·1)

40–44

39·7 (39·1–40·2)

34·9 (34·4–35·4)

37·6 (37·1–38·1)

30·5 (30·1–30·9)

45–49

31·9 (31·3–32·4)

28·4 (28·0–28·9)

31·8 (31·3–32·3)

30·3 (29·8–30·8)

50–54

29·4 (28·8–29·9)

26·2 (25·7–26·7)

30·0 (29·5–30·6)

26·2 (25·7–26·7)

55–59

31·1 (30·4–31·8)

23·0 (22·5–23·4)

25·3 (24·8–25·8)

23·0 (22·6–23·5)

60–64

35·4 (34·5–36·3)

22·0 (21·5–22·6)

21·7 (21·2–22·2)

17·7 (17·3–18·2)

Total

423·6 (416·8–430·5)

340·9 (335·7–346·2)

349·9 (344·5–355·3)

297·1 (292·4–301·9)

  1. aValues in parentheses represent 95% confidence intervals