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Table 3 Sensitivity analysis 1 – Influence of PDC rates on health care expenditures

From: Effects of adherence to pharmacological secondary prevention after acute myocardial infarction on health care costs – an analysis of real-world data

N = 9147

 

Estimate

Std. Error

t value

Pr(>|t|)

(Intercept)

 

− 4388.13

1956.20

−2.24

0.0249*

Age

55 < 65

366.80

667.03

0.55

0.5824

 

65 < 75

23.96

622.49

0.04

0.9693

 

≥ 75

− 1479.16

628.26

−2.35

0.0186*

Gender

female

− 182.06

298.09

−0.61

0.5414

BMI

underweight

760.97

1784.07

0.43

0.6697

 

overweight

−105.89

352.11

−0.30

0.7636

 

obese

− 177.73

380.95

−0.47

0.6408

BIMD 2010 (Q1 least deprived, Q5 most deprived)

Q2

− 342.96

410.99

− 0.83

0.4040

 

Q3

−745.28

441.27

−1.69

0.0913

 

Q4

− 299.33

436.92

−0.69

0.4933

 

Q5

− 781.20

414.84

−1.88

0.0597

Smoker

yes

−49.90

431.94

−0.12

0.9080

NYHA

1

2580.50

776.13

3.32

0.0009***

 

2

1378.37

463.25

2.98

0.0029**

 

3

2809.18

417.38

6.73

0.0000***

 

4

4422.92

440.04

10.05

0.0000***

DMP COPD

yes

1042.85

498.59

2.09

0.0365*

DMP asthma

yes

− 759.08

841.90

− 0.90

0.3673

DMP diabetes type 1

yes

2033.06

2326.11

0.87

0.3821

DMP diabetes type 2

yes

505.34

276.79

1.83

0.0679

deceased

yes

10,472.27

911.95

11.48

0.0000***

HMG assignments per month

 

1.23

0.24

5.18

0.0000***

Year after AMI

 

− 5722.92

162.81

−35.15

0.0000***

days insured

 

42.73

4.86

8.79

0.0000***

Angina pectoris

 

2027.02

270.66

7.49

0.0000***

Peripheral vascular disease

 

4179.64

382.42

10.93

0.0000***

Dyslipidemia

 

498.35

352.61

1.41

0.1576

Congestive heart failure

 

2090.90

339.30

6.16

0.0000***

Hypertension

 

1867.35

556.62

3.35

0.0008***

Dialysis

 

23,977.62

964.93

24.85

0.0000***

  

edf

Ref.df

F

p-value

s (PDC mean ACE inhibitors) male

 

1.04

1.04

0.01

0.9423

s (PDC mean ACE inhibitors) female

 

1.00

1.00

0.89

0.3465

s (PDC mean β-blockers) male

 

1.00

1.00

2.70

0.1003

s (PDC mean β-blockers) female

 

1.00

1.00

0.32

0.5704

s (PDC mean statins) male

 

1.65

1.65

1.87

0.0949

s (PDC mean statins) female

 

1.00

1.00

1.61

0.2044

s (PDC mean anti-platelet agents) male

 

2.49

2.49

18.84

0.0000***

s (PDC mean anti-platelet agents) female

 

3.38

3.38

6.26

0.0003***

s (PDC standard deviation ACE inhibitors) male

 

2.35

2.35

1.73

0.1356

s (PDC standard deviation ACE inhibitors) female

 

2.72

2.72

6.54

0.0005***

s (PDC standard deviation β-blockers) male

 

3.63

3.63

12.74

0.0000***

s (PDC standard deviation β-blockers) female

 

1.00

1.00

2.89

0.0893

s (PDC standard deviation statins) male

 

1.00

1.00

0.43

0.5129

s (PDC standard deviation statins) female

 

3.58

3.58

3.73

0.0107*

s (PDC standard deviation anti-platelet agents) male

 

4.05

4.05

4.77

0.0007***

s (PDC standard deviation anti-platelet agents) female

 

2.79

2.79

4.54

0.0059**

  1. R-sq. (adj.) = 0.333
  2. Abbreviations: AMI (Acute Myocardial infarction), BIMD 2010 (Bavarian Index of Multiple Deprivation, year 2010), BMI (Body Mass Index), DMP (Disease Management Program), HMG (Hierarchical Morbidity Group), NYHA (New York Hear Association), PDC (Proportion of days covered)
  3. Significane Levels:* p < 0.05 ** p <0.01 *** p < 0.001