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Table 3 Frequency of Risk Management Recommendations

From: At the intersection of precision medicine and population health: an implementation-effectiveness study of family health history based systematic risk assessment in primary care

Risk Management Recommendations N (%)
Monogenic Hereditary Related Recommendations 597 (31.6%)
 Genetic counseling for hereditary cardiac syndromes 107 (5.7%)
 Genetic counseling for hereditary cancer syndromes [26,27,28,29] 395 (20.1%)
 Genetic counseling for hereditary thrombophilia [30] 165 (8.7%
 Familial hypercholesterolemia testing [31] 66 (3.4%)
 Hemochromatosis iron studies and genetic testing [32] 3 (0.2%)
 Wilson’s disease genetic testing [33] 11 (0.6%)
 Alpha 1 anti-trypsinase deficiency genetic testing [34] 11 (0.6%)
Familial Cancer Related Recommendations 508 (26.9%)
 Ovarian cancer screening discussion [35] 32 (1.7%)
 Breast MRI screening [5] 58 (3.2%)
 Breast cancer chemoprevention [36] 109 (6%)
 Colonoscopy screening starting age < 50 and/or more frequently [37, 38] 241 (13.1%)
Common Chronic Disease Related Recommendations 1059 (56.1%)
 Aspirin for stroke prevention [39] 67 (3.6%)
 Diabetes screening 858 (45.4%)
 Abdominal Aortic Aneurysm screening [40, 41] 389 (20.6%)
 Calcium scoring CT for further cardiovascular risk stratification [4] 11 (0.6%)
 Lung cancer screening [42] 45 (2.4%)
  1. Because participants could receive more than one recommendation, percentages in the value column do not sum to 100