Table 1 Description of applied diagnosis-specific measurement instruments

Days with headache (last 4 weeks) [13]

Scale range from 0 to 28 days

Standardised Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ(S)) [14]

[for participants aged ≥18 years]

Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (AdolRQLQ) [17]

[for participants aged 12–17 years]

Scale range from not impaired at all [0 points] to severely impaired [6 points]

Minimal clinical important difference for both questionnaires: ±0.5 points

Standardised Asthma Quality of Life Questionnaire (AQLQ(S)) [15]

[for participants aged ≥17 years]

Paediatric Asthma Quality of Life Questionnaire – Standardised version (PAQLQ) [16]

[for participants aged 12–16 years]

Scale range from not impaired at all [1 point] to severely impaired [7 points]

Minimal clinical important difference for both questionnaires: ±0.5 points

Dermatology Life Quality Index (DLQI) [18]

[for participants aged ≥17 years]

Children Dermatology Life Quality Index (CDLQI) [19]

[for participants aged 12–16 years]

Scale range from no effect on patient’s life [0 points] to extremely large effect on patient’s life [30 points]

Minimal clinical important difference: ±4 points

Beck Depression Inventory II (BDI-II) [20, 21]

Scale range from minimal depression symptoms [0 points] to severe depression symptoms

[63 points]

Minimal clinical important difference: ±5 points

12-Item Short Form Health Survey Version 1 (SF-12) [22]

Online Screening questionnaire (for checking inclusion end exclusion criteria)