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Table 1 Description of applied diagnosis-specific measurement instruments

From: Effectiveness and cost-effectiveness of treatment with additional enrollment to a homeopathic integrated care contract in Germany

Diagnosis (ICD-10-Code) Measurement instruments
Migraine/headache (G43/ R51)
  Days with headache (last 4 weeks) [13]
  Scale range from 0 to 28 days
Allergic rhinitis (J30)
  Standardised Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ(S)) [14]
[for participants aged ≥18 years]
  Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (AdolRQLQ) [17]
[for participants aged 12–17 years]
  Scale range from not impaired at all [0 points] to severely impaired [6 points]
Minimal clinical important difference for both questionnaires: ±0.5 points
Asthma (J45)
  Standardised Asthma Quality of Life Questionnaire (AQLQ(S)) [15]
[for participants aged ≥17 years]
  Paediatric Asthma Quality of Life Questionnaire – Standardised version (PAQLQ) [16]
[for participants aged 12–16 years]
  Scale range from not impaired at all [1 point] to severely impaired [7 points]
Minimal clinical important difference for both questionnaires: ±0.5 points
Atopic dermatitis (L20)
  Dermatology Life Quality Index (DLQI) [18]
[for participants aged ≥17 years]
  Children Dermatology Life Quality Index (CDLQI) [19]
[for participants aged 12–16 years]
  Scale range from no effect on patient’s life [0 points] to extremely large effect on patient’s life [30 points]
Minimal clinical important difference: ±4 points
Depression (F32)
  Beck Depression Inventory II (BDI-II) [20, 21]
  Scale range from minimal depression symptoms [0 points] to severe depression symptoms
[63 points]
Minimal clinical important difference: ±5 points
All participants
  12-Item Short Form Health Survey Version 1 (SF-12) [22]
  Online Screening questionnaire (for checking inclusion end exclusion criteria)