Table 2 Matched comparisons of resource consumption and costs, during 1st hospitalization, between patients with healthcare acquired infection and their controls
From: Is it financially beneficial for hospitals to prevent nosocomial infections?
A - Central-line associated blood-stream infection (CLABSI) | ||||
|---|---|---|---|---|
Cases | Controls | Difference | p-value | |
N = 62 | N = 178 | |||
Mean | Mean (min, max)b | Mean (min, max)b | Mean (min, max)b | |
Antibiotic days | 34 | 13 (4, 23) | 21 (11, 30) | < 0.001 (< 0.001, 0.095) |
Imaging (number) | 18 | 6 (2, 10) | 12 (8, 16) | < 0.001 (< 0.001, 0.003) |
Cultures (number) | 16 | 5 (1, 10) | 11 (6, 15) | < 0.001 (< 0.001, 0.003) |
Blood tests (number) | 115 | 42 (15, 77) | 73 (38, 100) | < 0.001 (< 0.001, 0.015) |
Hospitalization days since inclusion | 34 | 14 (4, 25) | 20 (9, 30) | < 0.001 (< 0.001, 0.2) |
ICU days since inclusion | 22 | 3.9 (1, 7.3) | 18 (14.6, 20.1) | < 0.001 (< 0.001, 0.003) |
Antibiotic cost (USD) | 683 | 248 (52,572) | 435 (111,631) | 0.009 (< 0.001, 0.6) |
Total cost a (USD) | 6400 | 2376 (784,4512) | 4024 (1888,5616) | < 0.001 (< 0.001, 0.05) |
Total cost per day (USD) | 601 | 719 (157,1614) | − 118 (− 1013,444) | 0.63 (0.02, 0.02) |
B –Clostridium difficileinfection | ||||
Cases | Controls | Difference | p-value | |
N = 92 | N = 276 | |||
Mean | Mean (min, max)b | Mean (min, max)b | Mean (min, max)b | |
Antibiotic days | 18 | 6 (1, 13) | 12 (5, 17) | < 0.001 (< 0.001, 0.1) |
Imaging (number) | 3.1 | 1.7 (0.3, 3.4) | 1.4 (−0.3, 2.8) | 0.11 (0.002, 0.71) |
Cultures (number) | 5.1 | 1.7 (0.24, 3.8) | 3.4 (1.3, 4.86) | 0.003 (< 0.001, 0.26) |
Blood tests (number) | 33 | 16 (5.5, 28) | 17 (5, 27.5) | 0.02 (< 0.001, 0.54) |
Hospitalization days since inclusion | 16.4 | 8.6 (4, 14.2) | 7.8 (2.2, 12.4) | 0.02 (< 0.001, 0.53) |
Antibiotic cost (USD) | 202 | 88 (6,215) | 114 (−13,196) | 0.009 (< 0.001, 0.85) |
Total cost a (USD) | 1357 | 733 (204,1426) | 624 (−69,1153) | 0.047 (< 0.001, 0.83) |
Total cost per day (USD) | 101 | 93 (32,174) | 8 (−73,69) | 0.5 (< 0.001, 0.001) |
C- Surgical site infection | ||||
Cases | Controls | Difference | p-value | |
N = 76 | N = 215 | |||
Mean | Mean (min, max)b | Mean (min, max)b | Mean (min, max)b | |
Antibiotic days | 14.5 | 3.1 (1.9, 4.6) | 11.4 (9.9, 12.6) | < 0.001 (< 0.001, < 0.001) |
Imaging (number) | 5.2 | 2.3 (1.2, 3.6) | 2.9 (1.6, 4) | < 0.001 (< 0.001, 0.002) |
Cultures (number) | 3.6 | 0.58 (0.16, 1.2) | 3.02 (2.4, 3.44) | < 0.001 (< 0.001, < 0.001) |
Blood tests (number) | 25 | 9.6 (6, 14) | 15.4 (11, 19) | < 0.001 (< 0.001, < 0.001) |
Hospitalization days since inclusion | 8.3 | 5.5 (4.7, 6.4) | 2.8 (1.9, 3.6) | 0.002 (< 0.001, 0.032) |
Antibiotic cost (USD) | 148 | 18 (9,30) | 130 (118,139) | < 0.001 (< 0.001, 0.001) |
Total cost a,c (USD) | 6761 | 5860 (5701,6071) | 901 (690,1060) | < 0.001 (< 0.001, < 0.001) |
Deep infection (n = 39) | 8332 | 6852 (6697,7033) | 1480 (1299,1635) | < 0.001 (< 0.001; < 0.001) |
Superficial infection (n = 37) | 5104 | 4815 (4652,5056) | 289 (48,452) | 0.04 (0.03¸ 0.56) |