Table 2 Overview of the Cirrhosis Care Alberta (CCAB) evaluation methods
RE-AIM Domains | Outcomes | Measures | Data sources/ tools | Analytic Methods | Study Phase | ||
|---|---|---|---|---|---|---|---|
1 | 2 | 3 | |||||
Reach | Uptake | Proportion of care providers who participate in education interventions for the order set, | Program data, Administrative data, | Descriptive statistics | X | X | |
Proportion of cirrhosis patients being managed using the CCAB order set | Chart reviews | ||||||
Effectiveness | Clinical and Cost-Utility | I.e.. Cumulative hospital LOS and readmission rates per patient year, | Administrative data, | Interrupted time series, | X | X | |
Chart reviews | Incremental Cost-Effectiveness Ratio | ||||||
Cost of care (health system perspective) QALYs gained | |||||||
Patient reported outcome measures (PROMs) | Health-related quality of life, | Post-discharge phone surveys, EQ-5D and CTM questionnaires, | Descriptive and inferential statistics, | X | X | ||
Patient/family and provider experience | |||||||
Framework and thematic analyses | |||||||
Qualitative interviews | |||||||
Quality Measures | Quality of care (eg. appropriate prescribing of rifaximin, screening for frailty, time to post discharge follow up) | Chart reviews | Interrupted time series | X | X | ||
Adoption | Utilization | Number of hospital sites that use the orders sets/Number of hospital sites enrolled, | Administrative data, | Descriptive statistics, | X | ||
Qualitative interviews | Framework and thematic analyses guided by NPT and CFIR | ||||||
Processes and determinants of adoption | |||||||
Implementation | Feasibility | Processes and determinants of feasibility and acceptability from patients, caregivers and health care providers’ perspectives | Qualitative interviews | Framework and thematic analyses guided by NPT and CFIR | X | X | X |
Fidelity | Proportion of order sets prescribed that adhere to the three core-components of the standardized CCAB order set | Administrative data | Descriptive statistics | X | |||
Maintenance | Sustainability | Proportion of cirrhosis patients being managed using the CCAB order set 6 months after the research team has completed supported rollout | CCAB program implementation data, | Descriptive statistics, | X | ||
Framework and thematic analyses guided by NPT and CFIR | |||||||
Qualitative interviews | |||||||