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Table 2 Rates and single variable analysis of antibiotic prescribing by resident and care home characteristics

From: Antibiotic prescribing in UK care homes 2016–2017: retrospective cohort study of linked data

Variable

Number of antibiotic prescriptions

Resident years

Antibiotic prescriptions per resident year

Incidence rate ratio (95% CI)

Resident-level

 Gender

  Male

9200

3518

2.61

Ref.

  Female

19,489

7213

2.70

1.00 (0.95–1.06)

 Age

  65–74

3823

1507

2.54

Ref.

  75–84

10,159

3955

2.57

1.02 (0.94–1.10)

  85–94

12,649

4556

2.78

1.08 (1.00–1.17)

  95+

2058

713

2.89

1.16 (1.03–1.30)

 Type of care

  Residential

8539

3434

2.49

Ref.

  Nursing

20,071

7265

2.76

1.26 (1.17–1.35)

 Dementia

  No

17,325

5996

2.89

Ref.

  Yes

11,285

4703

2.40

0.86 (0.81–0.92)

 Respite care

  No

27,461

10,184

2.70

Ref.

  Yes

1228

547

2.24

0.89 (0.80–0.98)

 Entered care home during study period

  No

17,190

6742

2.55

Ref.

  Yes

11,499

3989

2.88

1.11 (1.06–1.17)

 Status at end of study period

  In home

10,573

4599

2.30

Ref.

  Permanently Discharged

2340

906

2.58

1.14 (1.05–1.24)

  Died

15,776

5226

3.02

1.47 (1.39–1.55)

 Number of reported infection episodes during study

  0

10,463

5405

1.94

Ref.

  1

5654

2206

2.56

1.52 (1.42–1.62)

  More than 1

12,572

3121

4.03

2.22 (2.07–2.37)

 Number of BNF chapters with repeated prescriptions (excluding antibiotics)

  0–1

852

1032

0.83

Ref.

  2–4

7971

3603

2.21

1.96 (1.77–2.16)

   5–7

16,390

5267

3.11

2.48 (2.25–2.73)

   8 or more

3476

829

4.19

3.19 (2.81–3.62)

Care home-level

 Country

  England

19,206

7441

2.58

Ref.

   Northern Ireland

3971

1313

3.02

1.20 (0.94–1.52)

   Scotland

4526

1726

2.62

1.04 (0.82–1.31)

   Wales

986

251

3.93

1.72 (0.99–3.00)

 Number of beds

   < 40

5708

1814

3.15

Ref.

  40–49

6930

2723

2.54

0.84 (0.67–1.06)

  50–59

7378

2894

2.55

0.82 (0.65–1.04)

  60+

8673

3300

2.63

0.87 (0.68–1.11)

 Median overall length of stay

   < 1 year

7041

2653

2.65

Ref.

  1–2 years

18,604

6952

2.68

1.02 (0.84–1.25)

   > 2 years

3044

1126

2.70

1.04 (0.77–1.41)

 Clinical staff per 100 residents

   < 10

6941

2643

2.63

Ref.

   10–19

15,143

5612

2.70

0.99 (0.81–1.22)

   20+

6605

2476

2.67

1.00 (0.79–1.26)

 Care staff per 100 residents

   < 60

7219

2554

2.83

Ref.

   60–79

16,211

6187

2.62

0.89 (0.73–1.09)

   80+

5259

1990

2.64

0.86 (0.67–1.11)

 Percentage residents with dementia

   < 10

6987

2320

3.01

Ref.

   10–80

18,411

7065

2.61

0.85 (0.70–1.03)

   80–100

3291

1346

2.44

0.82 (0.62–1.07)

 Percentage residents with nursing care

   < 10

3594

1351

2.66

Ref.

   10–80

13,278

5055

2.63

0.89 (0.69–1.14)

   80–100

11,817

4325

2.73

1.03 (0.80–1.33)

 Number of infection incidents per bed per year

  Less than 1

16,329

6548

2.49

Ref.

   1 to 2

8316

2887

2.88

1.14 (0.94–1.37)

   2 or more

4044

1297

3.12

1.24 (0.97–1.59)

  1. BNF British National Formulary, CI confidence interval, Ref. reference group