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Table 4 Reduced incidence of complications for the Spanish type 2 diabetes population with starting HbA1c > 48 mmol/mol (per 1000 population)

From: Improving management of glycaemic control in people with T2DM in primary care: estimation of the impact on the clinical complications and associated costs

> 48 to ≤ 58 mmol/mol 5 years 10 years 15 years 20 years 25 years
Eye disease
 BDR 5.5 22.8 33.1 38.8 36.0
 PDR 0.3 1.7 3.0 3.9 4.1
 ME 5.1 20.7 30.7 36.0 33.5
 SVL 0.1 2.4 5.7 8.7 10.6
 Cataract 1.8 6.3 8.8 10.2 9.3
TOTAL 12.7 54.0 81.3 97.6 93.5
Renal disease
 MA 8.0 31.0 45.0 52.0 47.3
 GRP 1.3 7.7 13.9 19.0 19.2
 ESRD 0.2 1.4 2.9 4.5 5.3
TOTAL 9.5 40.1 61.9 75.5 71.8
Diabetic foot
 Ulcer 3.5 23.2 42.0 53.5 52.9
 Recurrent ulcer 0.5 9.1 30.7 56.0 75.0
 Amputation ulcer 0.2 3.2 8.9 14.5 17.8
 Amputation recurrent ulcer 0 0.4 1.6 3.5 5.3
 Neuropathy 26.8 85.6 106.9 110.1 94.5
TOTAL 31.0 121.6 190.2 237.5 245.4
Cardiovascular disease
 CHF onset 0.5 5.2 7.7 8.8 8.4
 PVD onset 2.4 9.2 13.7 16.5 15.5
 Angina 0.5 6.0 9.0 10.1 9.7
 Diabetes mortality 0 0.9 3.0 5.7 8.0
 Stroke event −0.1 4.9 6.8 7.2 6.5
 Event fatality 1.4 17.4 27.8 32.7 32.9
 MI event 0.9 16.7 26.8 31.3 31.3
TOTAL 5.7 59.7 94.8 112.3 112.2
58 to ≤ 64 mmol/mol 5 years 10 years 15 years 20 years 25 years
Eye disease
 BDR 3.4 8.0 10.9 11.4 9.5
 PDR 0.3 0.8 1.3 1.5 1.3
 ME 3.1 7.7 10.6 11.2 9.3
 SVL 0.1 1.1 2.2 3.1 3.4
 Cataract 0.9 2.1 2.8 2.9 2.5
TOTAL 7.8 19.7 27.7 30.01 26.1
Renal disease
 MA 4.6 11.2 15.2 15.7 12.6
 GRP 0.9 3.1 5.1 6.3 5.5
 ESRD 0.1 0.6 1.1 1.5 1.5
TOTAL 5.7 14.8 21.5 23.5 19.6
Diabetic foot
 Ulcer 2.4 8.9 14.5 16.7 15.4
 Recurrent ulcer 0.4 4.5 12.0 19.9 24.7
 Amputation ulcer 0.2 1.5 3.3 5.0 5.6
 Amputation recurrent ulcer 0 0.2 0.7 1.3 1.9
 Neuropathy 14.7 29.4 34.7 32.3 26.4
TOTAL 17.7 44.5 65.02 75.2 74.0
Cardiovascular disease
 CHF onset 0.5 1.8 2.4 2.5 2.0
 PVD onset 1.3 3.1 4.4 4.5 3.8
 Angina 0.5 2.0 2.8 2.8 2.4
 Diabetes mortality 0 0.4 1.0 1.7 2.4
 Stroke event 0.4 1.7 2.1 2.1 1.7
 Event fatality 1.6 6.3 8.7 9.5 8.6
 MI event 1.6 6.2 8.4 8.9 8.2
TOTAL 6.0 21.6 29.9 32.1 29.2
64 to ≤ 75 mmol/mol 5 years 10 years 15 years 20 years 25 years
Eye disease
 BDR 6.9 11.5 14.5 16.3 15.4
 PDR 0.7 1.3 1.9 2.3 2.3
 ME 6.7 11.4 14.6 16.5 15.7
 SVL 0.6 1.9 3.4 4.8 5.6
 Cataract 1.9 3.2 3.9 4.4 4.1
TOTAL 16.9 29.3 38.4 44.2 43.1
Renal disease
 MA 9.8 16.2 20.4 22.8 21.2
 GRP 2.3 4.8 7.3 9.4 9.7
 ESRD 0.4 1.1 1.8 2.5 2.9
TOTAL 12.5 22.1 29.5 34.7 33.8
Diabetic foot
 Ulcer 5.9 14.3 20.9 24.8 24.6
 Recurrent ulcer 1.6 8.9 20.1 31.3 39.5
 Amputation ulcer 0.7 2.7 5.3 7.6 9.1
 Amputation recurrent ulcer 0.1 0.5 1.3 2.3 3.4
 Neuropathy 31.0 43.2 47.2 47.2 41.1
TOTAL 39.3 69.6 94.7 113.3 117.8
Cardiovascular disease
 CHF onset 1.9 3.0 3.6 3,8 3.6
 PVD onset 2.4 4.3 5.7 6.6 6.2
 Angina 2.1 3.3 4.0 4.3 4.0
 Diabetes mortality 0.2 0.7 1.7 2.7 3.8
 Stroke event 1.8 2.7 3.0 3.1 2.9
 Event fatality 5.6 9.5 11.6 12.7 12.5
 MI event 5.2 8.7 10.4 11.2 10.8
TOTAL 19.1 32.2 40.0 44.4 43.8
> 75 mmol/mol 5 years 10 years 15 years 20 years 25 years
Eye disease
 BDR 6.5 10.7 13.8 15.7 14.6
 PDR 0.7 1.3 1.8 2.3 2.3
 ME 6.4 10.6 13.8 15.9 14.9
 SVL 0.5 1.9 3.4 4.9 5.7
 Cataract 1.8 2.9 3.7 4.2 3.9
TOTAL 15.8 27.3 36.6 43.1 41.4
Renal disease
 MA 8.9 14.7 18.8 21.3 19.4
 GRP 5.1 10.0 14.9 19.3 22.9
 ESRD 0.5 1.2 2.1 3.0 3.4
TOTAL 14.5 25.9 35.8 43.5 45.6
Diabetic foot
 Ulcer 5.6 13.5 20.2 24.5 24.1
 Recurrent ulcer 1.4 8.4 19.8 32.0 41.3
 Amputation ulcer 0.6 2.6 5.2 7.7 9.4
 Amputation recurrent ulcer 0.1 0.4 1.3 2.5 3.7
 Neuropathy 28.5 39.7 43.7 43.8 37.0
TOTAL 36.0 64.6 90.2 110.5 115.5
Cardiovascular disease
 CHF onset 1.5 2.4 3.0 3.2 2.9
 PVD onset 2.1 3.8 5.3 6.4 5.9
 Angina 1.9 3.3 4.0 4.5 4.1
 Diabetes mortality 0 0.5 1.6 2.8 4.2
 Stroke event 1.4 2.4 2.8 2.9 2.7
 Event fatality 4.5 8.1 10.1 11.4 11.1
 MI event 4.4 7.7 9.6 10.5 10.0
TOTAL 15.8 28.3 36.4 41.6 41.0