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Table 2 Medical utilization and total cost between TRD and non-TRD (1000 KRW, 0.89USD)

From: Cost analysis of depression using the national insurance system in South Korea: a comparison of depression and treatment-resistant depression

 TRD
(N = 34,812)
Non-TRD
(N = 799,812)
P-valueTRD
/non-TRD ratio
Clinical medical utilization
Outpatients visitsmean ± SD95.2 ± 102.915.9 ± 41.3  
median (Q1, Q3)64 (28,128)3(1,11)  
ER visits number0.7(4.7)0.1(0.6)  
Hospitalization (N, %)17,246(49.5)149,901(18.7)  
Number of hospitalization (mean, SD)3.0 ± 3.61.7 ± 1.8  
Days of hospitalization
(mean, SD)
63.4 ± 145.028.9 ± 71.4  
Medical cost
Total costmean, SD6610.5 ± 11,126.71273.0 ± 4604.7< 0.00015.19
median (Q1,Q3)3326.2(1288.67157.0)142.0(42.9685.9)  
Related depression codemean, SD3461.6 ± 7670.8697.7 ± 3059.4< 0.00014.96
median (Q1,Q3)1384.3(543.93182.3)70.4(26.2258.3)  
 Patients with suicide code (N, %)4508 (12.95%)17,105 (2.14%)  
Total costmean, SD10,539.2 ± 14,061.14902.3 ± 9358.5< 0.00012.15
median (Q1,Q3)6178.4(3187.711790.9)2113.6(605.35414.7)  
Related depression codemean, SD5375.7 ± 9661.12138.5 ± 5714.6< 0.00012.51
median (Q1,Q3)2464.5(1115.44927.5)559.2(152.0,1923.7)  
 Patients without suicide code (N)30,304 (87.05%)782,777 (97.86%)  
Total costmean, SD6026.0 ± 10,496.51193.7 ± 4411.2< 0.00015.05
median (Q1,Q3)2955.8(1152.26458.3)135.7(41.9628.3)  
Related depression codemean, SD3176.9 ± 7286.0666.2 ± 2967.3< 0.00014.77
median (Q1,Q3)1255.0(501.42947.4)68.2(25.7242.2)  
  1. TRD treatment-resistant depression, SD standard deviation, Q1 first quartile, Q3 third quartile, ER emergency room, ECT Electroconvulsive therapy