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Table 2 Medical utilization and total cost between TRD and non-TRD (1000 KRW, 0.89USD)

From: Cost analysis of depression using the national insurance system in South Korea: a comparison of depression and treatment-resistant depression

 

TRD

(N = 34,812)

Non-TRD

(N = 799,812)

P-value

TRD

/non-TRD ratio

Clinical medical utilization

Outpatients visits

mean ± SD

95.2 ± 102.9

15.9 ± 41.3

  

median (Q1, Q3)

64 (28,128)

3(1,11)

  

ER visits number

0.7(4.7)

0.1(0.6)

  

Hospitalization (N, %)

17,246(49.5)

149,901(18.7)

  

Number of hospitalization (mean, SD)

3.0 ± 3.6

1.7 ± 1.8

  

Days of hospitalization

(mean, SD)

63.4 ± 145.0

28.9 ± 71.4

  

Medical cost

Total cost

mean, SD

6610.5 ± 11,126.7

1273.0 ± 4604.7

< 0.0001

5.19

median (Q1,Q3)

3326.2(1288.67157.0)

142.0(42.9685.9)

  

Related depression code

mean, SD

3461.6 ± 7670.8

697.7 ± 3059.4

< 0.0001

4.96

median (Q1,Q3)

1384.3(543.93182.3)

70.4(26.2258.3)

  
 

Patients with suicide code (N, %)

4508 (12.95%)

17,105 (2.14%)

  

Total cost

mean, SD

10,539.2 ± 14,061.1

4902.3 ± 9358.5

< 0.0001

2.15

median (Q1,Q3)

6178.4(3187.711790.9)

2113.6(605.35414.7)

  

Related depression code

mean, SD

5375.7 ± 9661.1

2138.5 ± 5714.6

< 0.0001

2.51

median (Q1,Q3)

2464.5(1115.44927.5)

559.2(152.0,1923.7)

  
 

Patients without suicide code (N)

30,304 (87.05%)

782,777 (97.86%)

  

Total cost

mean, SD

6026.0 ± 10,496.5

1193.7 ± 4411.2

< 0.0001

5.05

median (Q1,Q3)

2955.8(1152.26458.3)

135.7(41.9628.3)

  

Related depression code

mean, SD

3176.9 ± 7286.0

666.2 ± 2967.3

< 0.0001

4.77

median (Q1,Q3)

1255.0(501.42947.4)

68.2(25.7242.2)

  
  1. TRD treatment-resistant depression, SD standard deviation, Q1 first quartile, Q3 third quartile, ER emergency room, ECT Electroconvulsive therapy