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Table 3 Statistical difference between word-counts for local and imported NSAID for all products combined

From: Comparative evaluation of drug information leaflets for non-steroidal anti-inflammatory drugs in Palestine: local versus imported products

Variable

local Median [Q1-Q3]

Imported Median [Q1-Q3]

P value

Fold difference in medians

Therapeutic class

2.60 [2.00–4.50]

4.00 [4.00–8.50]

0.026

1.53

Mechanism of action

0.00 [0.00–4.25]

0.00 [0.00–17.00]

0.713

1

Indications

30.60 [19.50–42.75]

39.80 [18.50–74.50]

0.566

1.30

Drug dose

21.50 [12.50–51.25]

44.30 [28.30–65.25]

0.233

2.06

Duration of using

1.60 [0.00–5.25]

20.00 [2.35–27.60]

0.059

12.5

Missing dose

21.00 [16.65–32.75]

22.50 [0.00–28.40]

0.507

1.07

Maximum dose

6.00 [1.00–9.25]

7.00 [6.00–28.80]

0.169

1.16

Directions for use

33.50 [31.00–52.00]

30.00 [22.75–45.85]

0.200

1.11

Overdose and management

36.00 [35.80–41.80]

55.00 [36.80–93.75]

0.144

1.52

Warning and precautions

66.00 [31.00–92.30]

261.00 [183.00–425.50]

0.002

3.95

Effect on ability to drive and use machines

11.00 [0.00–14.80]

33.00 [20.00–61.50]

0.002

3.00

Contraindications

29.00 [19.00–84.00]

132.00 [100.00–152.75]

0.005

4.55

Adverse drug reactions

76.50 [60.25–104.50]

327.00 [213.20–503.75]

0.001

4.27

Drug-drug interactions

53.00 [49.00–67.05]

180.00 [118.25–257.85]

0.001

3.39

Drug-food interactions

4.30 [0.00–7.50]

18.50 [4.35–30.50]

0.053

4.30

Pregnancy considerations

19.00 [13.75–27.25]

45.00 [11.25–88.55]

0.170

2.36

Lactation considerations

13.00 [11.65–24.25]

9.00 [8.75–28.15]

0.595

1.44

Pediatric considerations

48.00 [35.65–64.75]

87.00 [56.25–120.95]

0.024

1.81

Geriatric considerations

0.00 [0.00–4.15]

42.40 [21.50–71.85]

0.002

>  42.40

Possibility of tablet splitting

0.00 [0.00–0.00]

5.00 [0.00–13.00]

0.010

>  5.00

Possibility of crushing and mixing with food or beverages

2.60 [1.50–3.15]

4.40 [3.00–6.10]

0.030

1.69

Shelf life

15.00 [10.60–16.00]

21.00 [16.35–27.00]

0.012

1.40

Storage

18.00 [14.50–32.00]

58.00 [43.85–78.05]

0.005

3.22