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Table 2 Combinations of comorbidities and 30-day potentially avoidable readmission

From: Multimorbidity and healthcare resource utilization in Switzerland: a multicentre cohort study

Combinations of comorbidities a

OR (95% CI)

Interaction b

Acute and unspecified renal failure

Solid malignancy

2.69 (1.81;3.99)

0

Pulmonary heart disease

Solid malignancy

2.48 (1.70;3.63)

0

Chronic kidney disease

Liver disease

2.40 (1.60;3.60)

Chronic kidney disease

Solid malignancy

2.39 (1.79;3.20)

0

Solid malignancy

Chronic obstructive pulmonary disease and bronchiectasis

2.36 (1.75;3.17)

0

Chronic kidney disease

Chronic obstructive pulmonary disease and bronchiectasis

2.29 (1.76;2.97)

0

Chronic kidney disease

Other nutritional, endocrine or metabolic disorders

2.23 (1.41;3.54)

0

Chronic kidney disease

Pulmonary heart disease

2.15 (1.64;2.83)

0

Esophageal disorders

Solid malignancy

2.15 (1.39; 3.33)

0

Liver disease

Solid malignancy

2.13 (1.41; 3.22)

0

Chronic kidney disease

Other and ill-defined heart disease

2.13 (1.45;3.13)

0

Chronic kidney disease

Other diseases of kidney and ureters

2.11 (1.41;3.16)

Chronic kidney disease

Thyroid disorders

2.09 (1.53;2.85)

0

Pulmonary heart disease

Chronic obstructive pulmonary disease and bronchiectasis

2.06 (1.51;2.80)

0

Chronic kidney disease

Chronic heart disease

2.02 (1.77;2.30)

0

Chronic heart disease

Systemic lupus erythematosus and connective tissue disorders

2.01 (1.26;3.21)

0

Paralysis

Other nervous system disorders

1.98 (1.39;2.82)

+

Chronic kidney disease

Nephritis, nephrosis, renal sclerosis

1.95 (1.55;2.47)

0

Epilepsy; convulsions

Solid malignancy

1.92 (1.25;2.95)

0

Chronic heart disease

Other lower respiratory disease

1.92 (1.18;3.13)

0

  1. Abbreviations: CI confidence interval, OR odds ratio, PAR potentially avoidable readmission
  2. a20 combinations with the highest OR for PAR
  3. b The sign "+"represents a significant more than multiplicative effect of the comorbidities found in the combination on the odds for PAR. A more than multiplicative effect means that the OR of the combination is larger than the ORs of the single comorbidities multiplied together. The sign "-"represents a significant less than multiplicative effect of the comorbidities found in the combination on the odds for PAR. A less than multiplicative effect means that the OR of the combination is smaller than the ORs of the single comorbidities multiplied together. The sign "0"means that there is no significant interaction