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Table 2 Combinations of comorbidities and 30-day potentially avoidable readmission

From: Multimorbidity and healthcare resource utilization in Switzerland: a multicentre cohort study

Combinations of comorbidities a OR (95% CI) Interaction b
Acute and unspecified renal failure Solid malignancy 2.69 (1.81;3.99) 0
Pulmonary heart disease Solid malignancy 2.48 (1.70;3.63) 0
Chronic kidney disease Liver disease 2.40 (1.60;3.60)
Chronic kidney disease Solid malignancy 2.39 (1.79;3.20) 0
Solid malignancy Chronic obstructive pulmonary disease and bronchiectasis 2.36 (1.75;3.17) 0
Chronic kidney disease Chronic obstructive pulmonary disease and bronchiectasis 2.29 (1.76;2.97) 0
Chronic kidney disease Other nutritional, endocrine or metabolic disorders 2.23 (1.41;3.54) 0
Chronic kidney disease Pulmonary heart disease 2.15 (1.64;2.83) 0
Esophageal disorders Solid malignancy 2.15 (1.39; 3.33) 0
Liver disease Solid malignancy 2.13 (1.41; 3.22) 0
Chronic kidney disease Other and ill-defined heart disease 2.13 (1.45;3.13) 0
Chronic kidney disease Other diseases of kidney and ureters 2.11 (1.41;3.16)
Chronic kidney disease Thyroid disorders 2.09 (1.53;2.85) 0
Pulmonary heart disease Chronic obstructive pulmonary disease and bronchiectasis 2.06 (1.51;2.80) 0
Chronic kidney disease Chronic heart disease 2.02 (1.77;2.30) 0
Chronic heart disease Systemic lupus erythematosus and connective tissue disorders 2.01 (1.26;3.21) 0
Paralysis Other nervous system disorders 1.98 (1.39;2.82) +
Chronic kidney disease Nephritis, nephrosis, renal sclerosis 1.95 (1.55;2.47) 0
Epilepsy; convulsions Solid malignancy 1.92 (1.25;2.95) 0
Chronic heart disease Other lower respiratory disease 1.92 (1.18;3.13) 0
  1. Abbreviations: CI confidence interval, OR odds ratio, PAR potentially avoidable readmission
  2. a20 combinations with the highest OR for PAR
  3. b The sign "+"represents a significant more than multiplicative effect of the comorbidities found in the combination on the odds for PAR. A more than multiplicative effect means that the OR of the combination is larger than the ORs of the single comorbidities multiplied together. The sign "-"represents a significant less than multiplicative effect of the comorbidities found in the combination on the odds for PAR. A less than multiplicative effect means that the OR of the combination is smaller than the ORs of the single comorbidities multiplied together. The sign "0"means that there is no significant interaction