|
Probability of TB Presumptive
|
0.022 (0.02–0.03)
|
0.046 (0.04–0.06)
|
[17, 34]
|
|
Probability of TB Test
|
0.61 (0.49–0.73)
|
0.82 (0.66–0.98)
|
[17, 34]
|
|
Probability of Positive TB test
|
0.08 (0.06–0.10)
|
0.13 (0.10–0.16)
|
[17, 34]
|
|
Probability of starting TB treatment
|
0.94 (0.75–1.13)
|
0.94 (0.75–1.13)
|
[17, 34]
|
|
Transition Probabilities
|
|
Probability of Successful TB treatment
|
0.77 (0.62–0.92)
|
0.75 (0.60–0.90)
|
[17, 34]
|
|
Probability of Failing TB treatment
|
0.02 (0.01–0.02)
|
0.04 (0.03–0.05)
|
[17, 34]
|
|
Probability of default during TB treatment
|
0.19 (0.15–0.23)
|
0.20 (0.16–0.24)
|
[17, 34]
|
|
Probability of Death during TB treatment
|
0.02 (0.01–0.02)
|
0.01 (0.008–0.012)
|
[17, 34]
|
|
Probability of dying from natural causes
|
Life tables
|
Life tables
|
[26]
|
|
Probability of relapse after successful treatment
|
0.03 (0.02–0.04)
|
0.03 (0.02–0.04)
|
[28]
|
|
Probability of mortality if no TB treatment
|
0.33 (0.26–040)
|
0.33 (0.26–0.40)
|
[29]
|
|
Probability of spontaneous cure
|
0.25 (0.20–0.30)
|
0.25 (0.20–0.30)
|
[30]
|
|
Cost
|
|
Cost of no TB symptom at screening
|
$2.15 (1.72–2.58)
|
$4.24 (3.39–5.09)
|
Additional file 1: Table S1
|
|
Cost if no TB test with positive symptom
|
$2.15 (1.72–2.58)
|
$4.24 (3.39–5.09)
|
Additional file 1: Table S1
|
|
Cost of screening and negative sputum test
|
$7.15 (5.72–8.58)
|
$11.24 (8.99–13.49)
|
Additional file 1: Table S1
|
|
Cost of screening and no treatment if smear positive
|
$82 (65.60–98.40)
|
$48 (38.40–57.60)
|
Additional file 1: Table S1
|
|
Cost of screening, tests and successful TB treatment
|
$223 (178.40–267.60)
|
$171 (136.80–205.20)
|
Table 2
|
|
Cost of screening, testing and TB treatment before loss to follow-up
|
$112 (89.60–134.40)
|
$86 (68.80–103.20)
|
Additional file 1: Table S1 (loss to follow up at 3 month of TX)
|
|
Cost of screening, testing and TB treatment before death from disease
|
$149 (119.20–178.80)
|
$114 (91.20–136.20)
|
Additional file 1: Table S1 (Death at 4 month of TX)
|
|
Disease weights (DWs)
|
|
DW for no TB treatment
|
0.0.331 (0.26–0.40)
|
0.0.331 (0.26–0.40)
|
[31]
|
|
DW of well state
|
0
|
0
| |
|
DW of death
|
1
|
1
| |
