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Table 1 Modeling inputs, assumptions and ranges of TB outcome for health states

From: The cost-effectiveness of incentive-based active case finding for tuberculosis (TB) control in the private sector Karachi, Pakistan

Probability Active Case Finding arm (lower and upper limit) Passive Case Finding arm (lower and upper limit) Reference
Probability of TB Presumptive 0.022 (0.02–0.03) 0.046 (0.04–0.06) [17, 34]
Probability of TB Test 0.61 (0.49–0.73) 0.82 (0.66–0.98) [17, 34]
Probability of Positive TB test 0.08 (0.06–0.10) 0.13 (0.10–0.16) [17, 34]
Probability of starting TB treatment 0.94 (0.75–1.13) 0.94 (0.75–1.13) [17, 34]
Transition Probabilities
 Probability of Successful TB treatment 0.77 (0.62–0.92) 0.75 (0.60–0.90) [17, 34]
 Probability of Failing TB treatment 0.02 (0.01–0.02) 0.04 (0.03–0.05) [17, 34]
 Probability of default during TB treatment 0.19 (0.15–0.23) 0.20 (0.16–0.24) [17, 34]
 Probability of Death during TB treatment 0.02 (0.01–0.02) 0.01 (0.008–0.012) [17, 34]
 Probability of dying from natural causes Life tables Life tables [26]
 Probability of relapse after successful treatment 0.03 (0.02–0.04) 0.03 (0.02–0.04) [28]
 Probability of mortality if no TB treatment 0.33 (0.26–040) 0.33 (0.26–0.40) [29]
 Probability of spontaneous cure 0.25 (0.20–0.30) 0.25 (0.20–0.30) [30]
Cost
 Cost of no TB symptom at screening $2.15 (1.72–2.58) $4.24 (3.39–5.09) Additional file 1: Table S1
 Cost if no TB test with positive symptom $2.15 (1.72–2.58) $4.24 (3.39–5.09) Additional file 1: Table S1
 Cost of screening and negative sputum test $7.15 (5.72–8.58) $11.24 (8.99–13.49) Additional file 1: Table S1
 Cost of screening and no treatment if smear positive $82 (65.60–98.40) $48 (38.40–57.60) Additional file 1: Table S1
 Cost of screening, tests and successful TB treatment $223 (178.40–267.60) $171 (136.80–205.20) Table 2
 Cost of screening, testing and TB treatment before loss to follow-up $112 (89.60–134.40) $86 (68.80–103.20) Additional file 1: Table S1 (loss to follow up at 3 month of TX)
 Cost of screening, testing and TB treatment before death from disease $149 (119.20–178.80) $114 (91.20–136.20) Additional file 1: Table S1 (Death at 4 month of TX)
Disease weights (DWs)
 DW for no TB treatment 0.0.331 (0.26–0.40) 0.0.331 (0.26–0.40) [31]
 DW of well state 0 0  
 DW of death 1 1