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Table 6 PRIMEtime CE sources and uncertainty distributions for baseline population data, costs, and utilities. All inputs are age and sex specific

From: PRIMEtime CE: a multistate life table model for estimating the cost-effectiveness of interventions affecting diet and physical activity

Parameter Data and methods
English population From Office for National Statistics census data, no uncertainty estimated [75].
Mortality rates Extracted from the Human Mortality Database, no uncertainty estimated [76].
Health sector costs Disease specific costs derived from NHS England programme budgeting data [77] and unrelated disease costs estimated using NHS England cost curves [78]. Using the same approach as Blakely et al., [34] health sector costs are assumed to be “moderately uncertain”, and therefore uncertainty is estimated using a generic multiplication factor across all health sector costs with a gamma distribution based on a normal distribution (mean 1, SD 0.1).
Societal costs Disease specific and unrelated productivity, social care, and wider societal costs estimated using a Department of Health tool published as a supplementary file in Claxton et al [79]. As with health sector costs, uncertainty estimated using a generic multiplication factor across all societal costs with a gamma distribution based on a normal distribution (mean 1, SD 0.1).
Utilities Baseline mean EQ-5D utility scores and disease specific decrements and their standard errors taken from Sullivan et al., with adjustments made for age and number of chronic conditions [80].