|Challenges related to using theory underpinning the TDFI approach||Accessibility of theory||Ease of which the theory can be understood and applied; access to support from theory experts.|
|Commitment to theory||Issues relating to participants’ understanding of the value of theory in eliciting behaviour change, and subsequent adherence to the use of theory at the prescribed stages of the research project.|
|Problem complexity||Issues around the processes leading to the outcome, here the processes leading to identification and referral of patients flagged at high risk of Lynch syndrome.|
|Practical (or context) challenges||Navigating the system (and system changes)||
Issues around governance and ethical regulatory requirements; understanding of local politics and tacit behaviours/cultural factors|
Constant changes affecting teams and processes, such as introduction of new IT systems.
|Stakeholder management||Issues related to multiple stakeholders across different disciplines and departments.|
|Perceptions of the problem||Issues around the perceived effort one should invest in the identified problem; lack of awareness about generalisability of solutions across contexts.|