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Table 5 Univariate and multivariate logistic regression models of the possible association between mortality (as dependent variable) and demographic as well as clinical features (as independent variables) of all patients in pre- and post-intervention groups

From: Clinical and economical impacts of guideline implementation by the pharmaceutical care unit for high cost medications in a referral teaching hospital

Variable

Mortality (n = 1539)

Discharged (n = 8302)

Univariate analysis

Multivariate analysis

OR (95% CI)

p

OR (95% CI)

p

Age (years)

Mean ± SD

50.04 ± 26.66

43.32 ± 25.99

1.010 (1.008–1.012)

< 0.001

1.008 (1.006–1.010)

< 0.001

Sex (%)

 Male

909 (59.06)

4943 (59.54)

1.020 (0.913–1.139)

0.727

 Female

630 (40.94)

3359 (40.46)

Type of ward (%)

 Internala

552 (35.87)

1343 (16.18)

0.873 (0.856–0.890)

< 0.001

0.880 (0.864–0.898)

< 0.001

 Surgicalb

160 (10.39)

1480 (17.83)

 Critical carec

346 (22.48)

1424 (17.15)

 Emergency

209 (13.58)

2106 (25.37)

 Pediatrics

272 (17.67)

1949 (23.48)

Admission diagnosis (%)

 Gastrointestinal diseases

437 (28.39)

2775 (33.43)

0.999 (0.967–1.01)

0.298

 Hematologic-oncologic diseases

255 (16.57)

1134 (13.66)

 Infectious diseases

241 (15.66)

905 (10.9)

 Cardiovascular diseases

164 (10.66)

806 (9.71)

 Neurologic diseases

133 (8.64)

868 (10.46)

 Kidney and urinary tract diseases

123 (7.99)

709 (8.54)

 Lung diseases

85 (5.52)

376 (4.53)

 Metabolic diseases

27 (1.75)

152 (1.83)

 Traumatic diseases

21 (1.36)

136 (1.64)

 Autoimmune disease

14 (0.91)

151 (1.82)

 Othersd

39 (2.53)

290 (3.49)

Intervention phase (%)

 Pre

737 (47.89)

4209 (50.69)

1.119 (1.004–1.248)

0.043

1.128 (1.009–1.262)

0.034

 Post

802 (52.11)

4093 (49.3)

  1. aIncluding general, nephrology, gastrointestinal, cardiac, and neurology wards
  2. bIncluding general surgery, cardiac surgery, neurosurgery, urology, plastic surgery, and orthopedic wards
  3. cIncludingintensive care and cardiac care units
  4. dIncluding rheumatologic diseases, skin/soft tissue diseases, electrolyte disorders, immune deficiency, and diseases of prematurity
  5. OR Odds ratio, CI Confidence interval