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Table 5 Univariate and multivariate logistic regression models of the possible association between mortality (as dependent variable) and demographic as well as clinical features (as independent variables) of all patients in pre- and post-intervention groups

From: Clinical and economical impacts of guideline implementation by the pharmaceutical care unit for high cost medications in a referral teaching hospital

Variable Mortality (n = 1539) Discharged (n = 8302) Univariate analysis Multivariate analysis
OR (95% CI) p OR (95% CI) p
Age (years)
Mean ± SD 50.04 ± 26.66 43.32 ± 25.99 1.010 (1.008–1.012) < 0.001 1.008 (1.006–1.010) < 0.001
Sex (%)
 Male 909 (59.06) 4943 (59.54) 1.020 (0.913–1.139) 0.727
 Female 630 (40.94) 3359 (40.46)
Type of ward (%)
 Internala 552 (35.87) 1343 (16.18) 0.873 (0.856–0.890) < 0.001 0.880 (0.864–0.898) < 0.001
 Surgicalb 160 (10.39) 1480 (17.83)
 Critical carec 346 (22.48) 1424 (17.15)
 Emergency 209 (13.58) 2106 (25.37)
 Pediatrics 272 (17.67) 1949 (23.48)
Admission diagnosis (%)
 Gastrointestinal diseases 437 (28.39) 2775 (33.43) 0.999 (0.967–1.01) 0.298
 Hematologic-oncologic diseases 255 (16.57) 1134 (13.66)
 Infectious diseases 241 (15.66) 905 (10.9)
 Cardiovascular diseases 164 (10.66) 806 (9.71)
 Neurologic diseases 133 (8.64) 868 (10.46)
 Kidney and urinary tract diseases 123 (7.99) 709 (8.54)
 Lung diseases 85 (5.52) 376 (4.53)
 Metabolic diseases 27 (1.75) 152 (1.83)
 Traumatic diseases 21 (1.36) 136 (1.64)
 Autoimmune disease 14 (0.91) 151 (1.82)
 Othersd 39 (2.53) 290 (3.49)
Intervention phase (%)
 Pre 737 (47.89) 4209 (50.69) 1.119 (1.004–1.248) 0.043 1.128 (1.009–1.262) 0.034
 Post 802 (52.11) 4093 (49.3)
  1. aIncluding general, nephrology, gastrointestinal, cardiac, and neurology wards
  2. bIncluding general surgery, cardiac surgery, neurosurgery, urology, plastic surgery, and orthopedic wards
  3. cIncludingintensive care and cardiac care units
  4. dIncluding rheumatologic diseases, skin/soft tissue diseases, electrolyte disorders, immune deficiency, and diseases of prematurity
  5. OR Odds ratio, CI Confidence interval