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Table 2 Comparison of monthly consumption of discussed medications and their relative monthly costs between pre-intervention and post-intervention groups

From: Clinical and economical impacts of guideline implementation by the pharmaceutical care unit for high cost medications in a referral teaching hospital

Variable Medication Pre-intervention group
(n = 4946)
Post-intervention group
(n = 4895)
Portion of reduction p
Number of medications used Albumin 5636 2771 50.83% < 0.001
Pantoprazole 7623 3027 60.29% < 0.001
IVIG 562 741 - 31.85%a < 0.001
Cost (USD) [mean ± SD or median (IQR)] Albumin 245,885 ± 18,616 108,689 ± 10,429 55.8% < 0.0001
Pantoprazole 62,399 (7769) 10,036 (1759) 83.92% 0.004
IVIG 69,234 ± 17,182 97,565 ± 19,164 −40.9%a 0.022
  1. aNegative value means that IVIG cost and number of use increased in the post-intervention phase compared to the pre-intervention period