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Table 1 Number of hospitalisations for confusion or falls avoided assuming cessation of one hypnotic

From: Reducing hypnotic use in insomnia management among Australian veterans: results from repeated national interventions

Hospitalisation for confusion (18)
Number of hypnotics Number of Confusion Person-Years Adjusted rate per 10 years (95% CI) Incidence rate ratio (95%) Adjusted rate difference per 10 years Adjusted rate difference per month Total hospitalisations for confusion avoided
0 156 21,491 0.049 (0.032–0.074) 1.00 (1.00–1.00)
1 118 16,773 0.052 (0.034–0.081) 1.07 (0.84–1.36) 0.0035 0.000029 1
2 76 5078 0.12 (0.074–0.18) 2.39 (1.79–3.19) 0.064 0.00054 11
3 24 1503 0.14 (0.078–0.24) 2.79 (1.78–4.38) 0.020 0.00016 4
4 10 454 0.21 (0.10–0.43) 4.26 (2.20–8.25) 0.072 0.00060 12
> = 5 17 200 0.94 (0.51–1.73) 19.35 (11.10–33.72) 0.733 0.0061 128
Hospitalisation for falls (15)
Number of hypnotics Number of Falls Person-Years Adjusted rate per 10 years (95% CI) Incidence rate ratio (95%) Adjusted rate difference per 10 years Adjusted rate difference per month Total hospitalisations for falls avoided
0 518 20,448 0.17 (0.13–0.23) 1.00 (1.00–1.00)
1 527 16,945 0.21 (0.16–0.28) 1.22 (1.08–1.38) 0.038 0.00031 7
2 246 5231 0.29 (0.22–0.40) 1.70 (1.45–1.99) 0.084 0.00070 15
3 to 4 108 1946 0.34 (0.24–0.48) 1.96 (1.58–2.43) 0.045 0.00037 8
> = 5 16 189 0.55 (0.31–0.96) 3.15 (1.90–5.23) 0.21 0.0017 36
  1. Data on number of confusion, number of falls, person-years, adjusted rates per 10 years and incidence rate ratio were taken from the two retrospective cohort studies which have been published previously (15,18)
  2. Total number of hospitalisation for confusion or hospitalisation for falls prevented were calculated by multiplying the number of patient-months of treatment avoided, which was 20,850, with the adjusted risk difference per month
  3. Note: We assumed cessation of one hypnotic (e.g. from two hypnotics to one) as a conservative estimate. The number of hospitalisation for confusion or hospitalisation for falls prevented would have been higher if patients had reduction of two or more hypnotics
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