| |
Hazard ratio
|
95% CI
|
P value
|
|---|
|
CCM status
|
0.82
|
0.75-0.91
|
< 0.0001
|
|
Age classa
|
|
75-85
|
1.89
|
1.67-2.15
|
< 0.0001
|
|
> 85
|
3.59
|
3.14-4.09
|
< 0.0001
|
|
Female gender
|
0.87
|
0.79-0.95
|
0.0020
|
|
Charlson index
|
1.39
|
1.31-1.48
|
< 0.0001
|
|
Treatment at enrolment
|
|
ACE-inhibitors or ARBs
|
0.77
|
0.68-0.86
|
< 0.0001
|
|
Beta-blockers
|
0.81
|
0.74-0.89
|
< 0.0001
|
|
Diuretics
|
1.98
|
1.67-2.34
|
< 0.0001
|
|
Geographic area
|
1.01
|
0.98-1.03
|
0.62
|
|
Previous HF hospitalization
|
1.12
|
1.02-1.22
|
0.015
|
- Predictors of death in the overall study population, as identified by multivariable Cox regression analysis. ACE angiotensin converting enzyme, ARBs angiotensin receptor blockers, CCM chronic care model, CI confidence interval
- aHazard ratios calculated vs age < 75 as a reference
