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Table 2 Hazard ratios for treatment drug prescriptions adjusted for period, sex, age, and comorbidity by the cox proportional hazard model

From: Impact of a direct-to-consumer information campaign on prescription patterns for overactive bladder

Characteristics Hazard Ratio (95% Confidence Interval)a
Age (continuous) 1.01 (1.001–1.02)*
Sex, female (versus male) 1.05 (0.80–1.37)
Charlson Comorbidity Index
 0 Reference
 1 0.90 (0.62–1.29)
  ≥ 2 0.94 (0.68–1.31)
Observation periodb
 Period 1 in Pre-Campaign Year (weeks 1–5) 3.22 (0.88–11.7)
 Period 2 in Pre-Campaign Year (weeks 6–10) 0.97 (0.20–4.80)
 Period 3 in Pre-Campaign Year (weeks 11–15) 2.27 (0.59–8.77)
 Period 4 in Pre-Campaign Year (weeks 16–20) 0.98 (0.20–4.85)
 Period 5 in Pre-Campaign Year (weeks 21–25) 0.98 (0.20–4.85)
 Period 6 in Pre-Campaign Year (weeks 26–30) 2.29 (0.59–8.87)
 Period 7 in Pre-Campaign Year (weeks 31–35) 0.99 (0.20–4.89)
 Period 8 in Pre-Campaign Year (weeks 36–40) 3.31 (0.91–12.0)
 Period 9 in Pre-Campaign Year (weeks 41–45) 1.00 (0.20–4.94)
 Period 10 in Pre-Campaign Year (weeks 46–50) Reference
 Period 1 in Year 1 (weeks 1–5) 2.99 (0.81–11.1)
 Period 2 in Year 1 (weeks 6–10) 1.34 (0.30–5.98)
 Period 3 in Year 1 (weeks 11–15) 1.34 (0.30–6.00)
 Period 4 in Year 1 (weeks 16–20) 7.09 (2.11–23.8)**
 Period 5 in Year 1 (weeks 21–25) 13.6 (4.21–44.1)***
 Period 6 in Year 1 (weeks 26–30) 4.27 (1.20–15.1)*
 Period 7 in Year 1 (weeks 31–35) 3.23 (0.87–11.9)
 Period 8 in Year 1 (weeks 36–40) 2.16 (0.54–8.66)
 Period 9 in Year 1 (weeks 41–45) 1.45 (0.32–6.48)
 Period 10 in Year 1 (weeks 46–50) 2.55 (0.66–9.86)
 Period 1 in Year 2 (weeks 1–5) 2.91 (0.77–11.0)
 Period 2 in Year 2 (weeks 6–10) 3.30 (0.89–12.2)
 Period 3 in Year 2 (weeks 11–15) 1.84 (0.44–7.72)
 Period 4 in Year 2 (weeks 16–20) 1.48 (0.33–6.62)
 Period 5 in Year 2 (weeks 21–25) 1.49 (0.33–6.65)
 Period 6 in Year 2 (weeks 26–30) 2.24 (0.56–8.97)
 Period 7 in Year 2 (weeks 31–35) 1.50 (0.34–6.72)
 Period 8 in Year 2 (weeks 36–40) 1.13 (0.23–5.60)
 Period 9 in Year 2 (weeks 41–45) 1.89 (0.45–7.91)
 Period 10 in Year 2 (weeks 46–50) 1.90 (0.45–7.95)
  1. *p < .05 **p < .01 ***p < .001
  2. aSample size, N = 1332
  3. bPre-Campaign Year (November 19, 2010 to November 18, 2011); Year 1 (November 19, 2011 to November 18, 2012); Year 2 (November 19, 2012 to November 18, 2013). Period 1 started on November 19 in each year