Table 2 Interrupted time series analysis by intervention period for the prescription rates of beta-blockers and ACEI/ARB
| Â | Beta-blockers | ACEI/ARB | ||||
|---|---|---|---|---|---|---|
Percentage (%) | 95% CI (%) | p-value | Percentage (%) | 95% CI (%) | p-value | |
Baseline trend | ||||||
 Prescription rate at month zero | 72.8 | 60.3 to 85.3 | < 0.001 | 89.2 | 76.7 to 100 | < 0.001 |
 Monthly change in prescription rates | −1.3 | −3.3 to 0.7 | 0.198 | −3.3 | −5.2 to − 1.4 | 0.001 |
Stage one intervention | ||||||
 Initial shift in prescription rates due to intervention (effects lagged by 1 month) | + 2.2 | − 11.3 to 15.8 | 0.747 | + 41.6 | 24.4 to 58.6 | < 0.001 |
 Subsequent monthly change in prescription rates | + 3.3 | 1.1 to 5.4 | 0.003 | + 1.1 | −1.4 to 3.6 | 0.377 |
Stage two intervention | ||||||
 Initial shift in prescription rates due to intervention (effects lagged by 1 month) | −4.6 | − 38.9 to 29.6 | 0.791 | + 13.7 | −7.8 to 35.1 | 0.213 |
 Subsequent monthly change in prescription rates | −1.8 | −6.2% to 2.5% | 0.415 | + 3.6 | 0.4% to 6.9% | 0.028 |