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Table 3 Genetic testing completion, results and use of information

From: Impact of a genetic counseling requirement prior to genetic testing

   GC Requirement Policy
Total
N (%)
Before
N (%)
After
N (%)
P-value
BRCA1/2 Testing Completion n = 1247 n = 297 n = 940  
 Yes 966 (77.5%) 243 (81.5%) 723 (76.2%) 0.13
 No 271 (21.7%) 54 (18.1%) 217 (22.9%)
 Unknown/Missing/Declined 10 (0.8%) 1 (0.3%) 9 (1%)
BRCA1/2 Test Results n = 966 n = 243 n = 723  
 Mutation 89 (9.2%) 26 (10.7%) 63 (8.7%) 0.55
 No Mutation 821 (85.0%) 204 (84.0%) 615 (85.3%)
 Results Uncertain 19 (2.0%) 6 (2.5%) 13 (1.8%)
 Do not Understand Results 8 (0.8%) 0 (0.0%) 8 (1.1%)
 Unknown 8 (0.8%) 2 (0.8%) 6 (0.8%)
 Missing/Declined 21 (2.2%) 5 (2.1%) 16 (2.2%)
Most commonly reported use of genetic testing resultsa n = 966 n = 243 n = 723  
 Talked with Family Members about Results 590 (47.3%) 147 (60.5%) 443 (61.3%) 0.42
 Routine Breast Cancer Screenings 329 (26.4%) 71 (29.2%) 258 (35.7%) 0.25
 Plan Cancer Treatment 173 (13.9%) 42 (17.3%) 131 (18.1%) 0.90
 Additional Breast Cancer Screening with MRI utilized 53 (4.3%) 10 (4.1%) 43 (6.0%) 0.38
 Surgery to Remove Breast or Ovaries to prevent Cancer 40 (3.2%) 11 (4.5%) 29 (4.0%) 0.59
 Other 39 (3.1%) 17 (7.0%) 22 (3.0%) 0.003
Most commonly reported reasons for why BRCA1/2 testing was not completeda n = 271 n = 54 n = 217  
 Insurance issues/requirements 165 (60.9%) 39 (72.2%) 126 (58.1%) 0.06
 Costs 129 (47.6%) 38 (70.4%) 91 (41.9%) 0.0002
 Testing not recommended by GC 56 (20.7%) 3 (5.6%) 53 (24.4%) 0.002
 Testing recommended for another family member 24 (8.9%) 4 (7.4%) 20 (9.2%) 0.79
 Likelihood low so decided against testing 18 (6.6%) 1 (1.9%) 17 (7.8%) 0.14
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